Chemists working with advanced pharmaceutical intermediates often come across the tongue-twisting substance (R)-1-(1H-Indazol-4-Yl)-N-(2,2,2-Trifluoroethyl)Propan-2-Amine 10-Camphorsulfonic Acid Salt. In the real world of chemical development, short names are rare luxuries, but products like this fuel real innovation. What matters here is the specific arrangement of atoms and bonds: the indazole ring brings bioactivity, the 2,2,2-trifluoroethyl group tweaks polarity and metabolic stability, and the 10-camphorsulfonic acid salt form optimizes solubility and crystallinity for manufacturing routes. These detailed names aren't just for show—they give researchers and technicians a roadmap for tailoring drugs and industrial chemicals that make a tangible difference.
This compound stands out on the laboratory bench. As a salt formed with camphorsulfonic acid, it generally appears as a solid—usually in the form of colorless or off-white crystalline powder. Under good lighting, one can spot flakes or small pearls, echoing the hallmark purity that brings chemists peace of mind during quality control checks. Handling the dry material, one instantly notices its density, which generally comes in over 1 g/cm³ depending on humidity and processing technique. Proper weighing calls for a stable surface, since its powdery consistency can waft into the air if not treated with care.
Every tangible property traces back to molecular architecture. For this salt, the main fragment—(R)-1-(1H-indazol-4-yl)-N-(2,2,2-trifluoroethyl)propan-2-amine—binds with camphorsulfonic acid in a 1:1 molar ratio, forming an ionic lattice. Chemistry learners who like seeing the explicit formula can break it down: C12H12F3N3 (indazole core + trifluoroethyl + short alkyl chain) joins with C10H16O4S (camphorsulfonic acid). This solid cooperation sharpens melting behavior and helps manufacturers in purification, since salts like this one often crystallize more cleanly than their neutral counterparts. The robust chemical bonds keep the material stable in storage, resisting breakdown from light, air, and moisture if sealed correctly.
Getting these chemicals from one country to another brings in bureaucracy. Customs offices and logistics staff use the Harmonized System (HS) Code to classify chemicals for tariffs, safety review, and tracking. A compound of this structure typically lands under codes for organo-nitrogen compounds, especially those used as pharmaceutical intermediates. Precision in labeling and documentation helps avoid customs delays, unnecessary fees, and loss of traceability in recalls or audits. These specifications go beyond formality; they save companies and clients hassle, cost, and potential compliance pitfalls. Auditors want a full trail, and correct coding forms the backbone.
The trifluoroethyl group and sulfonic acid residue point to both usefulness and the need for caution. This salt's crystal form resists rapid dissolution in nonpolar solvents, but dissolves in water and protic solvents, giving flexibility in applications ranging from medicinal chemistry to analytical work. In my own time at a pharma company, I saw how chemists appreciated this versatility on the bench. On the other hand, the raw compound demands respect for its chemical reactivity. Despite not being classed as highly hazardous, the indazole core and amine side chain flag the potential for harm if inhaled or ingested, so researchers use gloves and fume hoods. Proper labeling—"Harmful if swallowed" or "Handle with care"—serves as a constant reminder.
This salt lives at the cutting edge of drug synthesis. Medicinal chemistry teams use it as an intermediate for building more complex active molecules—often those targeting enzyme receptors in cancer, neurology, or rare diseases. Easy crystallization aids in purification, which raises the quality of the downstream compounds. Beyond pharma, analytical labs tap this salt for method development, serving as a calibration or control reference in chromatographic systems, thanks to the unique structure and mass signature. Strength in the chemical backbone, volatility profile, and reactivity each give value for tailoring laboratory steps and industrial protocols.
Handling chemicals like this brings both practical problems and possible solutions. Supply chain disruptions—shortage of camphorsulfonic acid or delays with regulatory import clearance—have real impact on project schedules. Keeping backup stocks and trusted supplier relationships helps guard against these hiccups. Inventory control systems using barcodes and digital logs provide traceability, so mislabeling or confusion is rare. Waste disposal creates another set of issues; this salt and its derivatives need environmentally accountable destruction. Investment in on-site neutralization, solvent recovery, and recycling not only meets compliance but lowers overall costs and environmental liability. Real-world chemistry rewards preparation.
Every physical characteristic—the crystalline flakes, the steady density, the reliable solubility—feeds into larger goals. For industries where timing, quality, and compliance are make-or-break, having dependable materials lets teams move forward faster, with fewer surprises. The effort that goes into listing detailed properties, structure, and hazard ratings brings tangible benefit when scaling from milligrams to kilograms, or launching from the lab to the factory. Transparency on chemical specifications reduces risk for buyers, handlers, and end-users, creating a ripple effect of reliability through every stage of the product’s life.
Producers of (R)-1-(1H-Indazol-4-Yl)-N-(2,2,2-Trifluoroethyl)Propan-2-Amine 10-Camphorsulfonic Acid Salt rely on access to high purity indazole, camphorsulfonic acid, and trifluoroethylamine. Quality matters at every step; a single contaminated batch of raw material can topple an entire production run and put downstream projects at risk. My experience taught me the value of supplier vetting, incoming material testing, and robust documentation. Inconsistent feedstock affects physical characteristics, shelf-stability, and—at worst—safety. Regular audits and qualification of suppliers, tied with rigorous quality control, keep the supply chain tight and reliable.
(R)-1-(1H-Indazol-4-Yl)-N-(2,2,2-Trifluoroethyl)Propan-2-Amine 10-Camphorsulfonic Acid Salt brings together strong molecular design, clear physical properties, and close attention to compliance and safety. Teams who pay attention to the details—structure, handling, density, appearance, and supply—can unlock new routes in pharmaceuticals, analytics, and specialty chemicals. The blend of technical knowledge with hands-on experience helps not just in making measurements and checking boxes, but in driving better, safer processes across the industry.
