This compound forms a specialized chemical structure, blending the distinctive pyridoisoquinoline core with a methanesulfonic acid component connected through a norbornanone bridge. The molecule brings together functional groups that include isobutyl, dimethoxy, and bromine substituents, leading to a product designed for specific roles in research or production settings. Unlike many standard raw materials, this chemical sits at the intersection of pharmaceutical research and advanced chemical synthesis. It brings together rigidity from its bicyclic base and reactivity from each substituent, offering options that simpler molecules miss. The presence of bromine at the 11-position gives the product unique reactivities, while the isobutyl group raises solubility and compatibility.
This material often appears as fine solid flakes, crystalline powder, or pearlescent granules, depending on storage and processing. It maintains stability in storage below ambient moisture, reflecting the robust structure from the norbornanone ring. In hands-on lab experience, the crystal form carries a white to pale yellow shade, sometimes off-white if exposed to open air. Granules tend toward higher density, while powder versions disperse easily in controlled solution work. The solid state resists compression, useful for transport but also requiring some care in weighing. Its melting point stays sharply defined, a sign of high purity. Density readings map around 1.35–1.45 g/cm³, which lines up with expectations for similar heterocyclic systems augmented by sulfonate groups.
Looking at the formula, C26H38BrNO7S, every atom provides a reason for why this molecule gets used where nothing else can substitute. Methoxy groups at the 9 and 10 positions wrap onto the isoquinoline, affecting both solubility in polar and non-polar solvents and influencing electron density on the core. The bicycle delivers extra volumetric occupancy, creating steric effects important in receptor binding or industrial synthesis. The mesylate tail, usually used to enhance salt formation and improve stability in storage, also impacts behavior during crystallization or solution work. With the exact three-dimensional configuration in (2R,3R,11Br) and (1S,4R) stereochemistry, enantiopurity plays a part in determining product fit in optically active environments.
A product like this must meet precise benchmarks to fulfill roles in research or active pharmaceutical ingredient development. Assay readings by HPLC consistently report over 98% purity, which keeps downstream syntheses efficient and byproduct levels low. Water content, most often under 0.5%, ensures shelf stability. Loss on drying checks, commonly set under 1%, give extra insurance against unwanted reactions or degradation. Granular and powder versions both handle well in laboratory spatulas and mechanical loaders. Volumetric weights remain consistent regardless of storage container, thanks to the structure’s rigidity. Hazard profile classifies it as a chemical for use only by trained professionals, not for public handling.
Custom classification falls under the general category for organic chemicals with heterocycle and acid group, often 2933 series for import/export paperwork. Discussions with customs or logistics teams always raise this number as a checkpoint for movement and taxes. Any shipment, domestic or international, follows this code to ensure proper legal handling. Specialists in the supply chain often ask suppliers for a standard reference to make sure the paperwork lines up with inventory. For substances bearing both a sulfonate salt and a complex bicyclic backbone, these codes remain reliable triggers for flagging special handling or value declarations.
Depending on the batch and method of isolation, this compound comes as hard crystalline flakes, loose powder, or spherical pearls. Formulation teams choose among these forms based on process compatibility—flakes go well in reactor additions, powder disperses easily, pearls limit dust exposure. In concentrated solution, the material disperses well in solvents such as DMSO and slightly less in water, thanks to the dual hydrophilic/hydrophobic character. Pearl and crystal forms travel best for bulk shipments, since they resist caking. Handling as a solution, technicians note the rapid dissolution in polar amides, allowing for efficient dosing in scaled synthesis.
In the lab, safety sheets call for strict protection when handling, because methanesulfonic acid salts and heterocycles can irritate skin and eyes. Teams keep gloves and protective gear ready. Mistakes here can trigger allergic responses or respiratory issues. Experience teaches that even small spills require prompt cleaning, as powder and tiny flakes can float and spread. Inhalation, accidental or otherwise, needs prompt medical response. Storage follows protocols for hazardous organobromine compounds: sealed containers, controlled humidity, and avoidance of direct sunlight all matter. Disposal through incineration with proper filtration fits most guidelines in advanced labs.
Discovery chemistry and advanced synthesis both tap into this molecule’s features. Presence of both a bromine and a mesylate group allows for cross-coupling, replacement, and redox reactions that create new derivative compounds. In practice, lab results show the base structure maintains integrity through extended syntheses, allowing stepwise building of more complex molecules. This resilience matters to medicinal chemists searching for new lead compounds, especially if the scaffold mimics natural products or known pharmacophores. Teams in both academic and industrial settings value these properties because exploring derivatives can lead to new medicines or performance materials.
The product’s molecular weight approaches 600 Da, which gives it suitable performance in processes seeking heavier or more robust intermediates. LogP readings suggest moderate hydrophobicity, which fits use in organic reactions and extraction processes. Melting points around 160–170°C provide reliable indicators for authenticity checks. Stability extends over a range of ambient temperatures, yet personal experience recommends cold storage for maximum lifespan. Density fits typical values for complex organics of this class—enough density for packaging but not so much as to complicate blending. The product resists oxidation and hydrolysis in neutral storage but shows degradation in acidic or alkaline extremes, justifying the use of buffered carriers in sensitive applications.
Best results come by storing in air-tight, light-resistant bottles, away from reactive metals and moisture. Teams label all containers with hazard information, purity, and storage recommendations, following regulations set by both OSHA and REACH. For lab use, experienced chemists dilute small amounts in compatible solvents before weighing to control dust. Engineers who work at scale switch to pearl or crystal forms to keep production lines clean and easy to manage. Unused product always returns to secure storage, and authorized staff log withdrawals to maintain traceability.
(2R,3R,11Br)-3-Isobutyl-9,10-Dimethoxy-1,3,4,6,7,11B-Hexahydro-2H-Pyrido[2,1-A]Isoquinolin-2-Ol (1S,4R)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Hept-1-Yl Methanesulfonic Acid provides much more than an academic curiosity. This is a specialty raw material—dense, well-characterized, technically demanding—serving as a backbone for discovery and application in demanding technical environments. It demands close attention to safe handling and regulatory details. Teams pushing boundaries in synthesis and drug development trace results back to robust starting materials like this one, with hands-on experience and best practices ensuring safety, reproducibility, and sustained innovation.
