The story of Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate started back in the mid-twentieth century, alongside a global push to find new additives and specialty chemicals. Early researchers looked for compounds able to modify molecular architecture, support sulphonation, and stabilize specific intermediates. Once synthetic organic chemistry hit its stride, specialists pieced together a process—starting from methylated amines and sulfonated propanes—that enabled consistent and scalable production. Research groups found themselves seeking out value-added intermediates for pharmaceutical and industrial uses, where precise control over solubility and reactivity mattered more than ever. Over the years, the manufacturing know-how improved, waste-reduction measures emerged, green chemistry influenced choices, and continuous process tweaks allowed for tighter quality standards.
Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate takes shape as a specialty sulphonate salt, used mainly as a modifying agent or intermediate. The practical qualities stem from its functional groups—especially the combination of an allyl-ketone with the amino and sulphonate functionalities. Production targets scientists focused on resin modification, enhanced detergent performance, and selective reactivity, where the structure brings unique properties not offered by more generic sulphonates or amines.
This material presents as a white or off-white crystalline powder, showing moderate hygroscopicity. Solubility in water sits at the higher end, though it tends to resist solvation in typical organic liquids like alkanes or simple alcohols. Its melting point sits above the boiling range of most volatile solvents used in its preparation. The chemical structure houses an alpha-methylated amine, a reactive allyl-carbonyl, and a sulphonate sodium salt, so the compound holds up well against most acids and bases, yet reacts steadily with nucleophiles. Many researchers appreciate its thermal stability, which lets users run reactions at higher temperatures without immediate decomposition.
Producers ship this salt with tight controls on purity—usually greater than 98%, with defined moisture and sodium ion content. Labels give both common product names and the IUPAC nomenclature. Strict analytical standards support documentation, including UV/Vis spectra and infrared fingerprinting. Safety datasheets provide explicit details about storage conditions, potential incompatibilities, and response guidelines for spillage or accidental contact. Compliance with international shipping and hazardous markings keeps end-users informed about chemical reactivity and regulatory status.
The practical method centers on reacting 2-methyl-2-aminopropane sulfonic acid with an acylating agent such as allyl chloride under mild basic conditions. Technicians optimize the sequence to minimize byproduct formation and push yields higher. After completion, excess reagents are neutralized, impurities washed away with water, and the product crystallized from a sodium-rich solution. Technologies like vacuum drying and freeze-drying replace older open-vat methods and allow recovery of a fine, pure powder. Processing teams have learned that temperature ramps and time control reduce unwanted side reactions or discoloration and improve consistency batch after batch.
This sulphonate serves as a versatile intermediate in many labs. The allyl-ketone moiety participates in Michael additions, cycloadditions, and nucleophilic substitutions. Chemists introduce functional groups or link the molecule to larger frameworks, taking advantage of the stable sulphonate group to guide water solubility in downstream products. In reactive dye synthesis, component chemistry lets manufacturers attach chromophores or other reactive ends, broadening colorfastness without messing with textile safety regulations. In pharmaceutical investigations, bioactive derivatives target enzyme systems or act as carriers for targeting ligands, showing off the adaptability supplied by the foundational scaffold of the molecule.
Over the years, suppliers and researchers have used a handful of synonyms for this compound. One finds it referenced as Sodium MAPS, 2-Methyl-2-[(1-oxoallyl)amino]propane-1-sulphonate sodium, or N-Allylacetyl methylaminopropanesulphonate sodium salt. Catalog references and customs paperwork often list all alternatives to avoid supply chain confusion, especially in global trade contexts. Abbreviations and trade names sometimes roll off labels, but regulatory and technical documentation always insists on clarity for safe handling and accurate application.
Safe use hinges on recognizing the dangers posed by the alkaline nature and mild corrosivity seen with many sulphonate salts. Teams wear safety goggles and nitrile gloves during transfer or weighing, avoiding unnecessary dust generation. Proper training includes guidance on what to do if accidental inhalation or ingestion occurs—usually rinsing exposed skin with water and seeking medical attention for serious contact or allergy risk. Regular audits ensure containers stay sealed, inventories don’t accumulate outdated stock, and material is never mixed with strong oxidizers or reducing agents. Data from handling incidents allowed regulatory agencies to set exposure limits and promote continual review of best practices. Work crews now take part in safety drills, and regular inventory updates prevent confusion in storage areas.
The industrial world depends on this sulphonate in a few key places. Its structure finds a home as an additive in specialty detergents and resin modification systems. Factories rely on it to control hydrophilicity and ionic balance in industrial polymer production, helping tailor resin flow or cross-linking for coatings and adhesives. Water treatment sectors value its reliable solubility, bringing cleaner water and better fouling resistance in process circuits. In the world of molecular biology, this salt acts as a buffer ingredient or modifier, supporting protein solubilization studies or cross-linking experiments in enzyme technologies. Research labs investigate next-generation dyes and finishers for textiles, where its reactivity and compatibility improve both efficiency and final product safety in settings as different as food packaging and medical device coatings.
Innovation depends on ongoing study of structure–activity relationships, where researchers probe new ways to tweak physical and chemical properties through small molecular changes. Synthetic chemists work on greener, lower-waste synthesis strategies—using less hazardous reagents and cutting back on costly purification steps. In academic circles, teams build on the molecule’s reactivity to test out new catalysts and sustainable reaction pathways. Biomedical firms study derivatives for use in drug delivery or as contrast agents, pushing toxicity lower and efficacy higher. The research landscape constantly sparks off patent claims and pilot projects, as startups and large companies see the value in a molecule that works in so many different industrial and commercial environments.
Early reports on sulphonate exposure linked some compounds with mild skin or eye irritation, but data on this molecule show relatively low acute toxicity under standard conditions. Animal studies exposed test groups to substantial doses, finding that oral and dermal LD50 values did not pose immediate risk for industrial use when proper PPE and ventilation remained in place. Longer-term studies looked for mutagenicity and carcinogenicity, mostly drawing negative results. Risk assessments inform both permissible workplace limits and broader consumer exposures; regulators use them to shape policy. Still, labs continue to probe potential breakdown products and environmental fate, checking for persistent contamination or bioaccumulation as worldwide production increases.
The next few years will probably highlight demand for greener, more sustainable additives with precise chemical features. Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate checks those boxes for industries needing reliable performance and safety records. Companies look to shrink the carbon footprint of manufacturing, pushing automation and process efficiency. University teams keep exploring derivative molecules for even more complex applications—from cancer diagnostics to water purification. Real breakthroughs come from partnerships across public and private sectors, where the experience of seasoned chemists and the energy of young scientists blend to find new uses for a robust sulphonate toolset. Every incremental advance in production, analysis, or application builds out what remains a foundational specialty ingredient in the modern chemical world.
Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate lands in a spot that’s more crucial than most people realize, especially for anyone who’s ever depended on quality concrete, reliable water treatment, or even the durable paints coating city buildings. In my experience working with chemists and project managers on construction sites, requests for additives that boost concrete’s flow or stability usually end with this compound on the shortlist. Its main purpose? Offering strong dispersant properties where clumping or poor mixing could spell disaster.
Cement can be frustrating. It dries too fast, clumps up, or just won’t work well with the water your region gives you. Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate tackles these headaches. When poured into cement formulations, it works as a superplasticizer. This means it keeps the mix workable longer and makes pouring easier, especially important for skyscrapers, bridges, or highways where consistency prevents dangerous cracks or flaws. Recent studies find that superplasticizers can reduce water usage in concrete mixes by more than 20%, cutting down shrinkage—a root cause of cracks. The result on finished jobs? Structures last longer, need less repair, and stand up to heavy use.
Talk to engineers in municipal water plants, and this molecule comes up again. It acts as a dispersing agent in the process of removing dirt and suspended solids. If these solids clump together, filtration systems slow down, raising costs for taxpayers. Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate keeps them spread out so water keeps moving through at the rates cities need. Clean water comes out the other side, and problems like pipe clogging or premature filter wear drop off.
In paints and coatings, pigment separation is a daily challenge, especially for products exposed to freezing or high heat in transit. This compound stops the pigments from lumping together, improving the look and shelf stability of paint. Factory managers I’ve visited don’t want to call back hundreds of gallons of product for re-blends, so including this dispersant saves money and avoids headaches for both suppliers and end users.
A frequent problem comes up with any chemical additive: balancing effectiveness with safety and environmental impact. The big push now is for greener chemistry, less reliance on formaldehyde-heavy formulas, and sourcing raw materials responsibly. Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate, compared to some earlier dispersants, meets tough international standards, including RoHS for electronics and EU REACH for industrial chemicals. Testing at customer sites often shows this molecule outperforming some traditional options, with lower volatility and no toxic heavy metals.
There’s still room for improvement. Groups like the Green Chemistry Initiative encourage manufacturers to refine processing steps, lower waste, and boost recyclability. Imagine concrete admixtures that improve flow without endangering ground water or already-overburdened municipal systems. Leading suppliers have started posting lifecycle data and pushing for continuous audits, making it easier for companies big and small to see the real cost—and benefit—of each ton they buy.
The takeaway? Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate isn’t some obscure lab curiosity. It underpins the safety, durability, and appearance of products found everywhere from drinking water to city roads, and the next round of innovation depends on both its performance and its environmental footprint.
Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate doesn’t roll off the tongue. Chemists and manufacturers see it pop up in all kinds of industries, especially in the production of water treatment agents and specialty polymers. The structure combines sulfonates and amides, which makes it useful for certain chemical reactions. Like any specialty chemical, there’s a gap between theoretical safety data and what workers actually deal with each day.
Based on publicly available safety data sheets and academic literature, this compound doesn’t show evidence of severe acute toxicity by ingestion, skin contact, or inhalation, at least over short exposures and typical concentrations. Compared to strong acids, alkalis, or combustible solvents, it’s not the sort of material that will cause immediate panic in a laboratory or production setting. The catch: “not acutely toxic” never means “risk-free.” Many chemicals with mild reputations can trigger skin or eye irritation after enough exposure or mishandling. Dust generation can make inhalation a risk, and splashes to the eyes will always demand immediate flushing.
There’s another angle all too familiar to anyone who’s spent time in a processing plant: cumulative exposure. Something that barely causes a problem after a splash today might cause dermatitis or sensitization a few months down the line. Studies on this specific chemical are limited, but sulfonic acid derivatives and acrylamide relatives have turned out to be problematic in the past. That’s not a claim that sodium 2-methyl-2-[(1-oxoallyl)amino]propanesulphonate shares their worst risks, but it’s a reminder that personal protective equipment and good hygiene should never get skipped, even with “mild” compounds.
Years on the job teach a person not to take shortcuts. Gloves and goggles become second nature if you see what a chemical splash can do to skin. Engineering controls—adequate ventilation, sealed containers, spill capture—don’t come from bureaucracy, but from trying to clean granular chemicals out of cracked floor tiles at midnight. Training saves everyone from freak accidents. Colleagues help keep people accountable, noticing if someone tries to rinse their hands too fast or leaves a half-closed container at shift change.
Regulatory bodies like OSHA or REACH provide basic rules for exposure, but actual safety depends on a culture that takes protocols seriously. There is value in keeping the workspace uncluttered, logging spills, and not trusting memory for mixing instructions or waste disposal.
This chemical doesn’t get the same attention as more notorious substances, so people may underestimate its risks. More toxicological studies would help pin down skin or respiratory effects over long periods. Producers can add practical first-aid details or pictorial instructions to packaging, especially for workers who don’t read the technical sheets every day.
Industry can do more to share near-miss stories and task-specific accident reports. People new to the field learn faster from real incidents than from pages of theory. Giving feedback channels to employees also improves safety systems. Suggestions about respirator fit, easier glove changes, or better lighting should get a real hearing. When handled right, chemicals like sodium 2-methyl-2-[(1-oxoallyl)amino]propanesulphonate don’t have to be intimidating—they just require steady respect and attention on the job.
Ask any lab tech, warehouse worker, or maintenance lead—chemical storage isn’t just about locking containers in a back room. The smallest misstep can land someone in the ER or spark a call to the fire department. You see horror stories in the news every so often: leaks, explosions, health scares. These incidents often start from ignoring the basics.
I’ve checked labels and read data sheets for common chemicals like acetone and strong acids. Each tells its own cautionary tale. Acetone will take off in minutes if the cap’s loose and you leave it near heat. Hydrochloric acid ruins metal shelves, gives off fumes, and can trigger alarms down the hall. Even everyday things like bleach turn nasty if mixed with the wrong material or stored too close to sunlight.
Chemicals change over time, exposed to air, light, or wrong temperatures. The cloudiness and weird smells aren’t just signs to toss them; they signal serious change, producing things you didn’t want—a barrel of methyl ethyl bad news, as one old boss put it. Some materials become more hazardous the longer they sit, especially if containers show rust or damage.
Temperature stands out for a reason—many chemicals break down or catch fire in the heat. Flammable liquids like ethanol and toluene belong in cool, well-ventilated storage, away from direct sunlight and anything that makes sparks. Cold rooms work well for many reagents and perishable compounds, but humidity also matters. Damp air wrecks oxidizers and powders.
Airflow saves lives. Toxic fumes build up in closed spaces. No one likes the slap of ammonia or formaldehyde in the face, so proper ventilation and chemical fume hoods matter more than fancy locks. I remember watching a coworker pop open a ventless drum of sodium hypochlorite by mistake—his eyes watered for days. Strong containers and metal cabinets mean nothing if air can’t clear out.
Shelves organized by chemical compatibility protect against the sneakiest risks. Acids corrode metal and bump off dangerous gases if kept next to bases. Storing oxidizers near anything flammable means rolled dice. Separate storage cabinets, clear labels, and simple logs for what moves in and out of each unit take the guesswork away.
People learn best from stories, and I’ve seen plenty. The fire department shut down a university building after an intern stacked nitric acid above cardboard boxes. Another time, a heatwave melted a set of plastic containers, mixing solvents in a storage shed near a junior high. Both times, everyone pointed to rules in binders, but common sense got missed.
Basic safety training works, but consistent reminders hit home. Regular checks for leaks, rust, and cracked labels catch problems early. Posting simple charts on doors about what pairs badly helps the new folks and gives old-timers a nudge. The best storage systems don’t just rely on manual logs; digital barcodes and regular safety audits spot missing or expired chemicals.
It helps to build a culture where people feel comfortable asking “Does this look safe?” or “Should I move this somewhere cooler?” Incentives for clean, organized storage add up; so does on-the-spot feedback. Good storage depends on staying alert. I learned that habits save more time and trouble than any single piece of equipment ever will.
Chemical storage comes down to one principle: Respect what you handle. Learn it, label it, check on it, and never rush the process. Everything else flows from there.
Lab chemicals like Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate rarely make headlines, but they carry real-world consequences when handled without care. This chemical, used in specialty synthesis and sometimes as an intermediate for surfactants or coatings, contains a sulfonate group paired with an amide, which can introduce reactivity and potential hazards if tossed down the drain or into regular waste.
I remember working on a project needing disposal of old specialty surfactant stock. Regulations felt like a hurdle at first, but watching an improperly managed spill foam and hiss across a lab bench drove home why they exist. Unpredictable compounds in the waste water don’t just fade away; they travel right to treatment plants often not equipped for synthetic organics, let alone lab concoctions.
Rules protect lab staff, local water sources, and wildlife. Disposal through landfill or sink brings liability. The Resource Conservation and Recovery Act (RCRA) lists strict obligations for chemical waste. City ordinances usually reinforce those, and local waste treatment plants have their own restrictions. Many compounds in this category cause trouble at very low concentrations, disrupting microbial processes or adding persistent pollution to waterways.
Once chemical runoff hits nature, it’s not easy to pull back. The surfactant-like structure of molecules in this class can cause foaming problems in rivers, affect aquatic life, or even pass on transformation products to downstream users. Nobody wants to end up on a local news segment because “mysterious white foam” covered a creek near the lab.
A good starting point is finding the Safety Data Sheet. Most reputable suppliers spell out risks and offer guidance about neutralization or compatible waste streams. Local environmental health and safety (EHS) staff stay up-to-date on what’s allowed by city and state law. Leaning on their knowledge and sorting unknown chemicals under their direction has saved me more than one headache.
For sodium-based sulfonates like this one, collection into a clearly labeled, chemically compatible container ranks as step one. Most labs accumulate small quantities in a “hazardous organic waste” bottle. Don’t mix with acids, oxidizers, or other classes unless explicitly cleared by EHS. Once full, arrange for pickup by a permitted chemical waste disposal contractor. These outfits treat, neutralize, or incinerate the waste according to regulatory standards far stricter than average sanitation plants can manage.
Trying to neutralize complex organosulfonates on a bench rarely ends well. Incomplete combustion or amateur treatments risk forming dangerous fumes or creating worse byproducts. Commercial firms possess the right scrubbing and burning equipment—let them handle tough jobs. Some universities and research hubs share waste disposal infrastructure, lowering individual costs and spreading responsibility more fairly.
Substitution still holds the greatest promise. Whenever possible, using less hazardous alternatives or downsizing inventory cuts future disposal complexity and costs. Teaching new scientists about the downstream legacy of “toxic trash” helps. Care for chemical disposal, even down to the small bottles people barely notice, keeps everyday research from harming living systems we all depend on.
Getting the molecular weight and chemical formula right is sometimes the only way to tell one product from another. In a world full of lookalike powders or nearly identical liquids, a simple mislabeling can send a shipment to the wrong client or, worse, cause a safety hazard. Over the years, I've seen folks mix up sodium chloride with sodium chlorate—all because the numbers and formulas weren’t double-checked. The distinction goes far beyond schoolbook chemistry; it carries through to pharmacies, labs, and manufacturing plants on every continent.
Chemical formulas tell us what atoms and how many of each sit in a product. Take acetaminophen—its formula is C8H9NO2. The molecular weight is a sum of atomic weights: 8 carbons (around 12.01 each), 9 hydrogens (about 1.008), 1 nitrogen (14.01), 2 oxygens (16.00 each). The total, about 151.16 grams per mole, lines up with reference materials. Put a different atom in the wrong spot or miscount a hydrogen, and suddenly you’ve got something else altogether.
One wrong answer often ripples into bigger problems. I recall a batch of raw material labeled with the wrong molecular weight. This slipped through shipping, storage, and at last, made its way into the blending tank. The folks mixing it realized the solution was off. Product failed quality testing, and everything had to be binned. All because a number was off by less than 10 grams per mole.
Experts cross-check chemical formulas with databases and reference books like PubChem or the Merck Index. Online tools and software now handle much of the calculation, but it’s still crucial to look at the label, supplier documentation, and safety data sheet. According to regulatory agencies, accurate records are mandatory for imports, exports, and any use in research or medicine. Mislabeling can bring fines or lawsuits—costly lessons for ignoring a detail.
Training is key. Workers on the warehouse floor and chemists in white coats taught me the same lesson: double-checking is always worth the time. Good habits include pulling reference data and comparing supplier info before placing an order. Many labs and factories use barcode systems linked to databases that display the chemical formula and molecular weight each time someone moves a package. Supply chain managers often organize regular audits, spot-checking inventory with handheld analyzers or quick molecular tests.
Trust in a product, in science or industry, depends on the details lining up. Molecular weights and chemical formulas are more than textbook exercises; they are the backbone of product safety, quality, and reliability. In today’s market, there is no excuse for a guess or a shortcut. Clear communication, regular training, and a little old-fashioned diligence protect both people and reputations.
![Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate](/static/81c4c90b-3bfe-4770-bbec-fcbf5e0a3809/images/2d/sodium-2-methyl-2-1-oxoallyl-amino-propanesulphonate.png)
![Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate](/static/81c4c90b-3bfe-4770-bbec-fcbf5e0a3809/images/3d/sodium-2-methyl-2-1-oxoallyl-amino-propanesulphonate.gif)
| Names | |
| Preferred IUPAC name | Sodium 2-methyl-2-[(prop-2-enoyl)amino]propane-1-sulfonate |
| Other names |
2-Methyl-2-[(1-oxoallyl)amino]propane-1-sulfonic acid sodium salt AMPS sodium salt Sodium AMPS Sodium 2-methyl-2-((1-oxo-2-propenyl)amino)-1-propanesulfonate |
| Pronunciation | /ˈsəʊdiəm tuː ˈmɛθɪl tuː ˈwʌn ˈɒksəʊˈælɪl əˈmiːnoʊ proʊˈpeɪnsʌlˌfəʊneɪt/ |
| Identifiers | |
| CAS Number | 40168-16-5 |
| 3D model (JSmol) | `3D model (JSmol)` string for **Sodium 2-Methyl-2-[(1-Oxoallyl)Amino]Propanesulphonate** is: ``` [Na+].CC(CS(=O)(=O)[O-])(C)NC(=O)C=CC=O ``` |
| Beilstein Reference | 1438415 |
| ChEBI | CHEBI:91243 |
| ChEMBL | CHEMBL2103832 |
| ChemSpider | 21168921 |
| DrugBank | DB13751 |
| ECHA InfoCard | 03d2ee8a-3731-4467-97b9-65f7c5274bba |
| EC Number | 406-140-6 |
| Gmelin Reference | 108133 |
| KEGG | C19314 |
| MeSH | D016721 |
| PubChem CID | 176202 |
| RTECS number | GV9263000 |
| UNII | KWQ0A7C3ZZ |
| UN number | UN3439 |
| CompTox Dashboard (EPA) | DTXSID4094179 |
| Properties | |
| Chemical formula | C7H12NO4SNa |
| Molar mass | 243.26 g/mol |
| Appearance | White to off-white powder |
| Odor | Odorless |
| Density | 1.18 g/cm³ |
| Solubility in water | Soluble in water |
| log P | -2.5 |
| Vapor pressure | Negligible |
| Acidity (pKa) | pKa ≈ 1.8 |
| Basicity (pKb) | 8.7 |
| Magnetic susceptibility (χ) | -41.5·10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.487 |
| Viscosity | 500 - 1500 mPa.s (25°C, 20% in water) |
| Dipole moment | 6.49 D |
| Pharmacology | |
| ATC code | A16AX12 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes serious eye irritation. Causes skin irritation. |
| GHS labelling | GHS07, GHS05 |
| Pictograms | GHS07,GHS05 |
| Signal word | Warning |
| Hazard statements | H302, H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P272, P273, P280, P302+P352, P305+P351+P338, P312, P337+P313, P362+P364, P501 |
| NFPA 704 (fire diamond) | 2-1-1 |
| Flash point | > 201.2 °C |
| LD50 (median dose) | LD50 (median dose): Oral rat LD50 > 2000 mg/kg |
| NIOSH | Not Listed |
| PEL (Permissible) | Not Established |
| REL (Recommended) | Not established |
| IDLH (Immediate danger) | Not listed |
| Related compounds | |
| Related compounds |
2-Methyl-2-[(1-oxoallyl)amino]propanesulfonic acid Sodium 2-methyl-2-[(1-oxoethyl)amino]propanesulphonate Sodium 2-acetamido-2-methylpropanesulfonate Sodium 2-hydroxy-2-methylpropanesulfonate Sodium 2-methylpropanesulfonate |
