Product Name: (R)-1-(1H-Indazol-4-Yl)-N-(2,2,2-Trifluoroethyl)Propan-2-Amine 10-Camphorsulfonic Acid Salt
SYNONYMS: Trifluoroethyl Indazole-Camphorsulfonic Acid Salt
Recommended use: Laboratory chemical, research and development
Manufacturer: Data available upon request by certified organizations or researchers
Emergency Contact: Refer to local and national emergency numbers
Product code: Internal codes used within R&D and analytical labs
Molecular formula: C15H16F3N3•C10H16O4S
Molecular weight: Calculable from formula components
Classification: Eye irritation, skin irritation, possible respiratory sensitizer
Signal Word: Warning
Hazard Statements: Causes moderate eye irritation. May cause skin reactions by prolonged exposure. May cause respiratory tract discomfort. Chronic exposure could affect the central nervous system in sensitive individuals.
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid dust generation, use in well-ventilated area, wash thoroughly after handling, wear protective gear at all times.
Routes of Exposure: Inhalation, skin, eye contact, accidental ingestion
Target Organs: Respiratory tract, skin, eyes, central nervous system
Chemical Name: (R)-1-(1H-Indazol-4-Yl)-N-(2,2,2-Trifluoroethyl)Propan-2-Amine 10-Camphorsulfonic Acid Salt
Purity: Typically greater than 97% (by HPLC)
Impurities: Typical residual solvents (dimethyl sulfoxide, methanol) present at trace levels
Other Ingredients: None intentionally added
CAS Number: Requires registration and research licensing
Camphorsulfonic Acid (CSAH): Typically provided at molar ratio corresponding to salt formation
Inhalation: Remove person to fresh air, monitor for respiratory distress. Provide oxygen if breathing difficulties present. Medical attention recommended.
Skin Contact: Immediately wash with soap and plenty of water (at least 15 minutes). Remove any contaminated clothing. Seek medical evaluation if irritation persists.
Eye Contact: Rinse thoroughly with plenty of water, lifting eyelids occasionally to ensure complete removal. Medical attention advised if discomfort continues.
Ingestion: Rinse mouth with water if person is conscious. Do not induce vomiting. Seek medical advice immediately, provide product SDS to healthcare professionals.
Note to Physicians: Symptomatic and supportive treatment advised for overexposure.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam as appropriate for surrounding area.
Specific Hazards: May emit toxic fumes of nitrogen oxides, sulfur oxides, hydrogen fluoride, carbon monoxide, carbon dioxide under fire conditions.
Protective Equipment: Firefighters require self-contained breathing apparatus and full turnout gear.
Precautions: Isolate fire area, stay upwind, avoid breathing combustion gases.
Special Procedures: Cool containers exposed to flame with water spray, prevent runoff from entering drains.
Personal Precautions: Use proper personal protective equipment including gloves, goggles, and suitable respirator. Prevent dust formation and provide adequate ventilation.
Environmental Precautions: Prevent further leakage, spillage, or release to drains or watercourses. Contain spill and avoid dust dispersal.
Methods for Cleanup: Carefully sweep or shovel up material, collect in sealed containers for verified disposal. Ventilate area and decontaminate spill site after completion.
Handling: Use only in certified chemical fume hood or well-ventilated area. Avoid inhalation, ingestion, or contact with skin and eyes. Keep container tightly closed and prevent dust accumulation.
Storage: Store in a cool, dry location with proper ventilation. Keep away from incompatible materials such as strong oxidizers and acids. Secure against unauthorized access. Store in labeled, tightly sealed containers guarded against moisture.
Specific End Uses: Chemical research and production use only—handled by trained professionals only.
Engineering Controls: Laboratory-grade fume hood, local exhaust, containment required in handling and weighing areas.
Exposure Limits: No occupational exposure limits available for this compound; minimize exposure by all practical means according to industrial hygiene principles.
Personal Protective Equipment: Lab coat, chemical-resistant gloves, splash-proof safety goggles required; respirators recommended where dusts or aerosols may be generated.
Hygiene Measures: Wash hands thoroughly after handling, refrain from eating or drinking in work areas, change contaminated clothing prior to exiting work area.
Appearance: White to off-white powder or crystalline solid
Odor: No significant odor under normal handling
pH: Not determined (solid state)
Melting Point/Range: Typically between 70-120°C (variability may occur due to salt/hydrate formation)
Boiling Point: Not applicable
Flash Point: Not established for solid
Solubility: Soluble in DMSO, limited water solubility likely (<5 mg/mL)
Density: Not measured, estimated around 1.2-1.3 g/cm³
Partition Coefficient (log Pow): Data not available
Vapor Pressure: Negligible at room temperature
Other Properties: Avoid exposure to strong oxidizers, acids, and bases
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Presents little risk of rapid decomposition; avoid strong oxidizing agents, acids, and bases
Hazardous Decomposition Products: Under thermal decomposition, releases nitrogen oxides, sulfur oxides, hydrogen fluoride, carbon oxides
Polymerization: No known hazardous polymerization expected under normal use
Incompatibility: Avoid contact with oxidizing substances and moisture
Acute Toxicity: Limited data on acute toxicity; low projected oral and dermal toxicity in animal studies based on chemical structure
Skin Corrosion/Irritation: Mild to moderate skin irritant reported in analog compounds
Serious Eye Damage/Irritation: Causes transient eye discomfort based on related substances
Respiratory Effects: Inhalation of dust may result in irritation to nose, throat, lungs
Chronic Toxicity: Chronic effects or carcinogenicity unverified—substitution of indazole and fluorinated ethylamines show some biological activity in animal models
Genotoxicity: Data not available; structurally related indazole compounds not classified as mutagenic in standard assays
Other Effects: Trifluoroethyl substituents can increase central nervous system penetration—prolonged exposure can lead to neurotoxic effects
Ecotoxicity: Toxicity to aquatic organisms likely based on structure; no direct studies available for compound
Persistence and Degradability: Fluorinated chains generally resistant to biodegradation; compound likely persistent
Bioaccumulation Potential: Data lacking, but risk of bioaccumulation exists with trifluorinated groups
Mobility in Soil: Limited data; some persistence in soil probable due to poor water solubility and resistance to hydrolysis
Other Adverse Effects: Improper disposal carries risk of long-term harm to aquatic habitats
Waste Treatment Methods: Dispose as hazardous laboratory chemical waste through licensed, regulated facility
Waste Residues: Incinerate at high temperatures with proper flue gas scrubbing systems
Contaminated Packaging: Triple rinse, then treat or incinerate per chemical waste SOPs
Environmental Precautions: Do not allow product, rinsate, or washwaters to enter natural water systems, sewers, or municipal landfills
UN Number: Not assigned—verify with shipper and regulatory agency to confirm status
Proper Shipping Name: Laboratory chemical, hazardous for transport depending on jurisdiction
Transport Hazard Class: Usually refers to class 6.1 (toxic) or class 9 (miscellaneous); consult hazardous materials advisor
Packing Group: Determined by response to exposure and risk of spill
Special Precautions: Secure packaging, secondary containment required for all shipments; declaration forms and MSDS must accompany shipments
Environmental Hazards: Mark as environmentally hazardous substance if applicable by shipping regulations
TSCA Status: May not be listed due to novel research status
REACH Registration: Pre-registered status possible, specific uses require communication with regulatory body
OSHA: Treated as hazardous chemical per OSHA Hazard Communication Standard
WHMIS (Canada): Classification determined after thorough workplace evaluation
Other Local/International Regulations: Import/export may need permits; consult authorities before shipping across borders
Label Elements: Conspicuous labeling with hazard and precautionary statements; GHS-compliant labels required for all primary and secondary containers
