Poly Methylene Co Guanidine Hydrochloride: A Ground-Level Look at a Modern Chemical

Historical Development

For decades, the world has chased better answers to persistent problems posed by microbes, fouling, and hazardous contaminants. Poly Methylene Co Guanidine Hydrochloride (PMCG-HCl) doesn’t trace its roots to accidents or one eureka moment. Chemists built the foundation in the 1980s, driven by institutional needs for breakthroughs in water treatment and textile applications. As regulatory bodies increased pressure against traditional toxic biocides, PMCG-HCl crept onto the stage. Unlike some chemicals, PMCG-HCl never caught a wave of hype; advancement moved slowly. Researchers watched as guanidine-based polymers took shape in labs, learning that fine tuning the methylene linkages quickly altered activity or stability. By the early 2000s, countries like Russia and China ramped up manufacturing capacity, mostly to address safety and environmental demands that traditional quats and phenols failed to solve. These days, PMCG-HCl gets attention not because of wild claims, but from steady performance and evolving regulation.

Product Overview

Poly Methylene Co Guanidine Hydrochloride does not turn heads with a wild molecular design. This polymer brings together guanidine groups and methylene chains, paired with hydrochloride for stability and solubility. Producers offer it as a clear-to-slightly yellow liquid or sometimes as a powder, branding it under plain names like “PMCG-HCl” and local product codes. The real draw sits in its reputation for solid antimicrobial punch without the severe toxicity profile of older cousins like formaldehyde-releasing compounds. Over time, industry moved this polymer into applications starting from water disinfection, heading next into surface sanitization, and reaching out into leather, paint, and textile treatments. Every time I watched operators switch from chlorinated agents to PMCG-HCl, the reduction in noxious fumes spoke more loudly than any marketing copy.

Physical & Chemical Properties

PMCG-HCl arrives as a high-molecular-weight, water-soluble polymer. Its appearance never gives much away: an almost colorless liquid, sometimes showing slight viscosity. It dissolves easily in cold or warm water, giving no smell and mild acidity. This polymer resists temperature swings far better than many organic biocides, staying stable up to 120°C and breaking down only near 200°C. The hydrochloride form adjusts pH and boosts shelf stability, a reason many suppliers keep the chloride salt as standard. Unlike many competitors, PMCG-HCl holds up in hard water, resists alkaline breakdown, and doesn’t foam up under agitation—big advantages for large-scale systems in food, textile, or paper plants. These properties make it adaptable and easier to introduce into existing lines compared with polyethyleneimines or biguanides.

Technical Specifications & Labeling

Producers rely on concentration marks, molecular weight boundaries, and purity levels to differentiate PMCG-HCl products. High-quality grades run at 20-30% active ingredient, with residual monomer levels kept below 0.5%. Labels must communicate shelf-life, storage temperatures (usually 5-35°C) and clear hazard statements per global harmonized system (GHS) standards. Most regulatory agencies make little room for ambiguity; each drum or tote lists batch number, manufacturing date, and intended application class. Specification sheets read like checklists for those in charge of water safety: viscosity, color, pH range, solubility, microbial log reduction tests, and a short line about chloride content. The documents support the work of operators in the field—nobody I know ever memorizes the fine details, but they trust certificates of analysis and published SDS documents before turning on a pump.

Preparation Method

Producers scale up PMCG-HCl using step-growth polymerization. This means guanidine salts—often guanidine carbonate—go in with formaldehyde and hydrochloric acid under heat and pH control. The recipe calls for hours of careful stirring, constant sampling, and neutralization once chain growth stops. Factories have tried tweaks: run high pressure, drop in co-monomers to change functionality, or slow the reaction to minimize side chains. Keeping by-products low keeps waste and regulatory hassle to a minimum. Over the years, companies built closed-loop scrubbers to handle off-gassing and acidic mist, earning more trust in safety programs. My own experience watching batch operators sample and measure polymer length has shown that consistency doesn’t come by accident—well-managed lines turn out cleaner, safer polymer. Final product runs through multi-stage filtration and concentration systems, checked before any packaging for visible particles or pH drift.

Chemical Reactions & Modifications

The backbone of PMCG-HCl invites modification. Producers tinker with functional side chains drawn from amines, carboxylic groups, or even linked bioactive agents to tweak everything from antimicrobial potency to film-forming properties. In some regions, adding hydrophobic methyl groups helps the polymer persist longer on treated surfaces. Blending with polyquaternary ammonium compounds pushes efficacy against bacteria, viruses, and even some molds. Sometimes chemists alter the counterion, swapping chloride for acetate or sulfate to meet local disposal rules or skin-contact regulations. PMCG-HCl rarely interacts with most process chemicals in unwanted ways, but mixing with high-oxidation agents (like bleach) can lead to breakdown or reduced biocidal power. Overdosing doesn’t bring much benefit, as I’ve seen in plant dosing trials—there comes a point when more doesn’t mean better and can lead to waste or increased corrosion, so careful titration always outpaces “more is better” thinking.

Synonyms & Product Names

Researchers call this polymer by several names, which makes tracking studies tricky. Common synonyms include Poly(iminomethylene)guanidine hydrochloride, Polyhexamethyleneguanidine, and simplified codes like PHMG-HCl. Trade names pop up based on region—“Guanistat,” “PolyGuanidine Hydro,” “Polyguard”—and individual factories mark each lot with custom codes or regulatory registration numbers. Regulatory paperwork usually groups PMCG-HCl with other polyguanidines, so reading supporting toxicology and registration files takes patience. Anyone handling product selection learns quickly to parse competing labels and recognize the polymer by its molecular structure and test data, more than by whatever a sales department prints on the drum.

Safety & Operational Standards

PMCG-HCl shows far less toxicity to humans than phenolic biocides or oxidizing agents, but operators must follow real precautions. Skin contact rarely brings acute harm but repeated exposure leads to mild dermatitis—so gloves and goggles never gather dust in facilities where this chemical is used. Inhalation of mist poses some risk, especially during blending or cleaning line maintenance. International standards demand both proper PPE and local extraction ventilation whenever large tanks get filled or emptied. Disposal must address the polymer’s moderate environmental persistence, routed through neutralization tanks or biologically active wastewater systems before final release. Plant managers respect local and international chemical handling laws, including China’s GB/T 29602-2013 and the European REACH regulations. Incidents remain rare in plants that track containers, train new hires, and enforce inspection routines after every shift; I have seen strong safety records linked directly to how companies set up monitoring, not just to the chemical’s inherent risks.

Application Area

PMCG-HCl finds use in places that balance need for reliable disinfection and respect for environmental limits. Water treatment dominates markets in Russia, China, and parts of Europe, where the polymer controls bacteria and biofilm in potable and process water without excessive sludge. Hospitals and food-processing plants add this polymer to surface sanitizers since it tackles bacteria, yeasts, and even viral particles with low residue and limited off-smell. Leather, paper, and textile facilities use PMCG-HCl during wet-processing stages to stop microbe growth and improve shelf-life of treated stock. Specialty paint suppliers use the polymer to prevent spoilage during can storage. Even in some swimming pool products, PMCG-HCl replaces copper or silver to cut down hazardous waste. Its broad-spectrum control never erases the need for good engineering; only proper dosing, pH adjustment, and routine monitoring protect against misuse and resistance buildup. Watching PMCG-HCl introduced to systems with long-standing biofilm, I saw plant operators measure a real drop in contamination after stubborn months spent fighting slime by less effective means.

Research & Development

Research still pushes the envelope for PMCG-HCl, searching for the sweet spot of longer life and broader activity. Teams across Asia and Europe run controlled trials, testing blends with enzymes or natural extracts to lower overall chemical loads. The move to biodegradable modifications looks promising, since reducing environmental accumulation stays one step ahead of regulatory crackdowns. Toxicology groups work with newer modeling tools, mapping gene response in human and bacterial systems so risk profiles don’t get set by rough animal studies alone. In recent years, research journals flagged some safety gaps, particularly in the context of inhalation exposure—fueling calls for better monitoring sensors in plants using PMCG-HCl at scale. Industry alliances pool data on polymer breakdown, pushing for robust analytical methods that find every trace of residue in finished water and processed goods. The pursuit never chases hype, but instead focuses on incremental proof—better log reductions here, lower off-target toxicity there.

Toxicity Research

PMCG-HCl skirts the catastrophic toxicity profiles that haunt many early disinfectants, but it doesn’t earn a free pass. Published data shows low dermal and oral toxicity in mammals, making it less dangerous than traditional phenols or aldehydes. In aquatic systems, the polymer poses moderate hazard—high doses stunt algae and invertebrate development—which triggers strict effluent monitoring in jurisdictions with sensitive streams or fishing economies. Human safety data points to rare irritation, but reports from Russia and China highlighted rare allergic responses in heavily exposed workers, a sign that routine monitoring and allergy screening should remain standard practice for major users. Chronic toxicity studies show no clear evidence of carcinogenicity or genetic damage, backing its use in food-contact settings with proper rinsing and air control. For anyone working behind the scenes in regulatory affairs, reading ten years of data led to the conclusion that measured, controlled use keeps problems in check, while casual or poorly managed dosing exposes weak spots much faster.

Future Prospects

Looking forward, PMCG-HCl sits at the front edge of biocidal technology, but faces sturdy competition from enzymatic products, emerging peptides, and highly engineered quaternary compounds. Regulators plan to push harder on environmental controls, so producers invest in greener modifications and tighter effluent treatment systems. Market expansion leans toward regions with rising standards for potable water and food safety, particularly in Pacific Asia, Africa, and parts of Latin America. Research focuses on tailoring molecular weight and substitution patterns to improve breakdown after use, aiming for a biodegradable profile without losing microbe control. Corporate buyers lean toward chemicals like PMCG-HCl not out of nostalgia but because it consistently combines safety, performance, and regulatory fit better than most alternatives on the market. In my role assisting plant startups, I see chemical managers grill suppliers over decomposition, byproduct risks, and real toxicity impact, driving technical staff on both sides to ground each claim in real test data and raw field evidence. As technology, markets, and regulations shift, PMCG-HCl must keep moving forward—no chemical gets to coast on yesterday's reputation once public trust and environment step up as the main stakeholders.




What is Poly Methylene Co Guanidine Hydrochloride used for?

Understanding Poly Methylene Co Guanidine Hydrochloride

Poly Methylene Co Guanidine Hydrochloride doesn’t show up much in daily conversation, but it has a firm spot in fields that often don’t get the spotlight. This substance mostly finds its place in disinfection, preservation, and water purification. It acts as a biocide, showing strong antibacterial and antiviral power, and these qualities have led to its use across hospitals, water treatment plants, and even food processing lines.

How Poly Methylene Co Guanidine Hydrochloride Protects Health

Bacteria and viruses thrive wherever moisture collects. In my time working with small clinics, I noticed that keeping surfaces and equipment clean proved vital for limiting infections. Poly Methylene Co Guanidine Hydrochloride offers a way to cover that base. It bonds to cell membranes in germs, breaking them down. Hospitals use it to clean tools that touch blood, saliva, or open wounds because they need something that really stands up to disease threats.

This compound isn’t just for big city hospitals. Remote clinics lacking pricey disinfection gear still need reliable options, especially during outbreaks. Poly Methylene Co Guanidine Hydrochloride helps bridge that gap. Its ability to stay stable under tough conditions means it works both in winter’s damp basements and the steamy heat of summer clinics—without breaking the budget. That last point matters in communities already stretched thin.

Clean Water and Public Safety

Clean water stands as one of the building blocks of good health. I’ve seen how polluted wells can unravel a town’s wellbeing. Poly Methylene Co Guanidine Hydrochloride steps into this fight by clearing water of bacteria and viruses. Municipal water systems and portable field units both rely on it to get water safe before it leaves the tap. Research shows that treatment with this compound wipes out common troublemakers like E. coli and staph. For rural areas and places hit by disaster, this takes worry off the table and lets families drink and cook with confidence.

Keeping the World Fed

Food preservation matters just as much as water, especially when supply chains face delays or refrigeration fails. I’ve watched food industry teams scramble during blackouts, trying to keep products from spoiling and spreading illness. Poly Methylene Co Guanidine Hydrochloride enters the scene as a preservative, fighting the mold and bacteria that make food unsafe.

Even after food leaves the factory, this compound helps keep things safe on the shelves. Bread stays free from fuzzy growth, juices hold their taste longer, and processed meats keep their color and freshness. With foodborne illness still a leading cause of hospital visits, this protection provides real peace of mind.

Balancing Safety and Environmental Impact

The rise of stronger chemicals always sparks debate over health and environmental risks. Experts regularly test Poly Methylene Co Guanidine Hydrochloride to track its breakdown in soil and water. So far, it tends to break apart quickly enough to avoid lasting buildup. Still, pushing for more responsible use and tighter monitoring makes sense—especially with chemicals that touch water and food.

Building Trust Through Transparency

Poly Methylene Co Guanidine Hydrochloride offers practical answers for some of today’s hardest public health questions. People want trust in the products that keep them safe. Honest labeling, easy-to-find safety guides, and regular third-party safety checks all help reassure shoppers and communities. These steps keep the conversation open between workers, regulators, and the public.

Is Poly Methylene Co Guanidine Hydrochloride safe for humans and pets?

What Is Poly Methylene Co Guanidine Hydrochloride?

Poly Methylene Co Guanidine Hydrochloride, often shortened to PMCG or PMCG-H, works as a disinfectant found in hospitals, water purification, household sprays, and sometimes pet products. Companies promote it for antimicrobial properties, saying it fights bacteria, molds, and some viruses. Unlike strong-smelling bleach or alcohol, its chemical nature means it leaves almost no odor and gets praised for minimal skin irritation. The promise of a gentler cleaner tempts many households.

Looking at Human Health Risks

The question of human safety depends on contact and concentration. In my work at a veterinary clinic, I’ve watched staff reach for a PMCG-based spray to wipe down cages, thinking it’s safer for allergic people or pets. Few read the small-print warnings or consider the cumulative effect of long-term exposure. Scientific papers show acute skin irritation or mild eye burns from pure concentration. Inhaling the fine mist can trigger coughing, sore throat, or headaches, especially in spaces lacking good airflow. Long-term studies remain scarce, but regulatory groups warn not to swallow it or use it as a skin sanitizer. The science community keeps asking for more peer-reviewed research with clear long-term results.

How Safe Is It for Pets?

Pet owners chase answers about cage guards, grooming wipes, or water bowl treatments containing PMCG. I’ve met people using diluted PMCG in fish tanks—hoping to keep water clean. Cats, dogs, parrots, and reptiles often groom their fur or drink from recently cleaned bowls. No one wants chemicals building up in tiny bodies. Some studies point to limited side effects in mice and birds at very low concentrations. Yet accidents from overuse happen in homes and animal shelters. My friend’s cat developed red, scaly lips after licking a PMCG-wiped tray, only improving after they flushed the area and stopped using the spray. Label instructions warn not to let animals ingest it, and that’s good advice—accidental overexposure poses a real risk to sensitive species.

What Regulators Say

Regulation varies by country. The US Environmental Protection Agency includes PMCG on its disinfectant list for surfaces, but only with proper dilution and application. The European Chemicals Agency assigns hazard warnings about eye and skin damage. Both agencies tell manufacturers to post safety data sheets and ask users to wear gloves and eye protection. Health Canada stopped sales of certain versions for household use, citing possible human and pet toxicity. These guidelines signal caution: dilute it right, keep it out of mouths, flush away residue, and think about better-ventilated cleaning routines.

Moving Toward Safer Cleaning

Good cleaning culture matters as much as the chemical itself. I try to pick products with straightforward safety labels and reach out to manufacturers. At home and in clinics, I aim for natural soap where possible, check for pet-safe options, and wash away residues well. For tanks and kennels, water and vinegar clean up most messes without unknown side effects. If you pick up a PMCG-based product, look for detailed instructions and warnings. Reach out to veterinarians or pediatricians if unsure—especially with pets already prone to allergies or breathing issues. Measures like ventilating rooms, wearing gloves, and storing chemicals out of reach help keep every family member safer, human or animal.

How is Poly Methylene Co Guanidine Hydrochloride applied or used?

The Basics Beyond the Label

Some chemicals step out from obscurity by showing up in more jobs than you’d guess. Poly Methylene Co Guanidine Hydrochloride belongs in that camp. It’s a mouthful to say but sinks right into everyday life — especially in cleaning and water work. This compound gets a nod from scientists and regulators because it brings serious antimicrobial punch without sending up all the red flags people usually expect from older disinfectants.

Cleaning Up the Scene

Walking into a hospital, airport, or even a gym, you probably pass through surfaces wiped with something containing this compound. Janitors and facility managers mix it up in dilutions tailored to fighting whatever bacteria or viruses threaten that space. Nobody frets about ruined equipment or runners slipping on sticky floor residue; the beauty comes from how the solution dries clean without leaving a scratchy film. What stands out for staff is that they get protection and peace of mind with every swipe, minus skin irritation that lingers after using something harsher, like bleach.

Reaching Into Water

I’ve watched small communities wrestle with keeping drinking water safe. Shoving barrels of chlorine into wells turns the tap water harsh, metallic, sometimes undrinkable. Poly Methylene Co Guanidine Hydrochloride steps in as a gentler alternative. In the right hands, a technician measures out specific doses and stirs the solution into storage tanks. The benefit runs twofold: water tastes normal, and bacteria meet a quick end. The towns see fewer outbreaks of stomach bugs, and there’s less need to fuss over offensive smells or rusty-looking water, which means more trust in every glass poured at the table.

Personal Care and Fabric Uses

This isn’t just about mopping up messes or keeping water safe. Textile factories, where I’ve seen the insides, rely on it to keep fabrics germ-free after dyeing and finishing. They don’t want colors to fade or fabrics to weaken under stronger chemicals, so this solution keeps material vibrant, prolonging the life of clothes and preventing unwanted odors down the line. Backpackers and gym-goers might not realize their odor-resistant shirts and towels owe a debt to smart antimicrobial application at the mill.

Risks Managed With Care

All chemicals come with rules. Here, the advantage is the ability to get real disinfection at lower doses, trimming risks to kids, pets, and anyone with allergies. Catastrophic spills or dangerous fumes don’t fill the incident logs. Factory managers keep tanks labeled, gloves on, and rooms ventilated, sticking to established safety sheets — and so the community stays clear of the worst-case scenarios that older alternatives have caused. By respecting the guidelines handed down from regulators, everyone stays safer.

Broader Impact and Smarter Choices

Poly Methylene Co Guanidine Hydrochloride doesn’t demand expensive equipment or complicated training for users. In over-stressed clinics or public transit, where cleaning time feels stolen from patient care or tight schedules, that simplicity matters. As climates shift and new bacteria emerge, facilities get pressed to do more with less. Widespread adoption brings relief for overworked teams while protecting vulnerable people, all through a few practical shifts in cleaning routines and water safety. That’s a change many can feel with every safe visit or drink of water.

What are the storage and handling precautions for Poly Methylene Co Guanidine Hydrochloride?

Getting Storage Right

Poly Methylene Co Guanidine Hydrochloride often shows up in water treatment and as a disinfectant. Even though it solves tough microbial problems, keeping it stable isn’t something to take for granted. If you have ever worked in a lab, you know moisture and uncontrolled temperatures can throw a wrench in even the best plans. This chemical prefers a cool, dry place, away from direct sunlight. Constant sunlight causes chemicals to break down sooner, which cuts their usefulness and can create safety risks. From personal experience, I’ve seen containers left near a window go cloudy and degrade faster than those kept in a cabinet or storeroom. Putting this compound on a high shelf in a climate-controlled room doesn’t just save on costs; it also makes workplaces safer in the long run.

People sometimes choose makeshift containers or transfer chemicals between bottles that look safe enough. With Poly Methylene Co Guanidine Hydrochloride, this shortcut invites bigger problems. The proper container—usually one made of high-density polyethylene with a tight-fitting lid—keeps the substance stable. Metals or glass can react or crack. I’ve seen emergency cleanups where poor storage choices led to leaks, prompting an avoidable weekend spent scrubbing floors and handling unexpected paperwork.

Managing Risks in Handling

No one likes to rush through chemical handling, but small shortcuts can have ripple effects. Poly Methylene Co Guanidine Hydrochloride causes irritation if it touches skin or eyes, and inhaling powder or dust stings the airways. Gloves—nitrile or chemical-resistant—aren’t just a box to tick. Proper eye protection shields against the rare splash that otherwise leads to a miserable afternoon. Respirators, though less glamorous than a standard mask, protect during bulk handling or any process likely to stir up dust. It’s tempting to skip, especially if “nothing has ever gone wrong,” but stories pile up showing even routine days can flip quickly.

Spill response supplies belong close to any area using this chemical. In my own work, fast access to absorbent materials and neutralizing agents proved vital more than once, especially in older facilities with less-than-perfect ventilation. Extraction fans can help, but strong, steady airflow is what minimizes risk of inhaling fumes or dust.

Secure Areas and Staff Training

The most effective safety programs train people to recognize risks before a situation escalates. Staff who know exactly where spill kits and emergency showers are respond more calmly and avoid injuries. Regular drills never felt thrilling to anyone, but I’ve seen teams handle real emergencies with confidence thanks to repeated practice.

Access control matters too. Label storage clearly. Post hazard signs. Make sure people can’t wander in without permission or signoff. In small organizations, inform new team members right away. Documenting storage dates and inspecting containers each month reveals leaks or clumping early. I learned from a mentor that a simple inventory checklist reduces surprises—and lets you address issues before they grow.

Responsible Disposal and Environmental Impact

Disposing of Poly Methylene Co Guanidine Hydrochloride in regular trash or pouring it down the drain causes more harm than many realize. Waste haulers and water treatment plants weren’t built for chemicals like this. Adhering to local waste management rules and coordinating with hazardous waste collection services protects the environment and public health. Following these practices signals respect for the workplace, the team, and the wider community—something every responsible handler owes to those around them.

What are the possible side effects or hazards of Poly Methylene Co Guanidine Hydrochloride?

Looking Past the Label

Stories about chemical disinfectants float across headlines every season. Poly Methylene Co Guanidine Hydrochloride (PMCGH) gets its share of attention in healthcare, water treatment, and even home sanitizing products. Scientific journals mention long words and complicated graphs, but the real risks of using PMCGH sit closer to home. From labs to living rooms, this chemical presents genuine concerns worth understanding.

What Happens When You’re Exposed?

Users rarely pause to think about inhaling fumes or touching products with bare skin. I’ve seen coworkers suffer mild rashes and eye irritation from handling PMCGH without gloves. Direct contact often leads to irritation — red bumps, dryness, burning sensations. The eyes get watery, red and swollen after a splash or a spray. In bigger doses or repeated exposure, people face chest tightness or even asthma-like coughing. This doesn’t come as a surprise after reading reports out of chemical safety workshops.

Our lungs and skin do a lot of heavy lifting every day, but PMCGH makes the job tougher. The chlorine content in this compound brings immediate disinfection power, but also a punch to delicate tissue. Asthma groups and dermatology clinics report a spike in complaints after PMCGH cleansers become popular during cold and flu season. Inhaling mist or particles, especially in walled-off rooms, can set off headaches, nausea, and persistent breathing trouble.

What About Drinking Water?

Many cities use PMCGH to treat water systems. It works fast against bacteria, but chemical residues can stick around. Sensitive folks notice funny tastes or stomach cramps after regular exposure. I’ve talked with parents who worried about chronic diarrhea or anxiety in their children, not realizing the link to their tap. Official water council studies flag PMCGH as safe below strict limits, but real-world accidents and overuse land people in clinics year after year.

Building Resistant Germs

A larger hazard slips beneath headlines. Overreliance on strong disinfectants breeds tough, resistant bacteria. Years ago, I saw a hospital switch to PMCGH for every surface. At first, infections dropped. Before long, patients caught strains unaffected by standard doses. This isn’t fiction — microbial resistance happens in dental offices, food plants, and swimming pools. Experts from the World Health Organization warn that careless use can make common treatments useless in the long run.

Seeking Safer Choices

People want clean spaces, but many don’t realize sharing kitchens and bathrooms with PMCGH brings risks along for the ride. Simple steps matter. Workers should always use gloves and eye protection. Families need better information on safe storage and the dangers of mixing chemicals. Public agencies must keep updating safety limits — and hold chemical companies accountable for clear labeling.

Schools, hospitals, and city offices push for non-toxic cleaning options when possible. Some are switching to mechanical cleaning, UV treatment, and safer natural solutions. The shift doesn’t cost as much as some vendors claim. Connected communities and well-informed staff make the difference.

PMCGH works in many scenarios, but safety depends on respect and restraint. Sharing honest stories, demanding better standards, and choosing wisely keeps everyone safer now and down the road.

Poly Methylene Co Guanidine Hydrochloride
Poly Methylene Co Guanidine Hydrochloride
Names
Preferred IUPAC name poly(imino methylene hydrochloride)
Other names PMCG
Polymethylene guanidine hydrochloride
Polyaminopropyl biguanide
Polyhexamethylene guanidine hydrochloride
PHMG-HC
Pronunciation /ˌpɒli mɛˈθɪliːn koʊ ɡwəˈnɪdiːn haɪˌdrɒklaɪd/
Identifiers
CAS Number 141492-61-3
Beilstein Reference 3589794
ChEBI CHEBI:78515
ChEMBL CHEMBL1201587
ChemSpider 31653917
DrugBank DB11205
ECHA InfoCard 03d726bf-0a8d-499f-9fdc-d63bd2c48e45
EC Number 85409-23-0
Gmelin Reference 67630
KEGG C18609
MeSH D000071243
PubChem CID 10221956
RTECS number SL8575000
UNII X1R5K8QN79
UN number UN3439
CompTox Dashboard (EPA) DTXSID30873093
Properties
Chemical formula (C7H18N4·HCl)n
Molar mass 307.67 g/mol
Appearance White to light yellow powder or granular
Odor Odorless
Density 1.15 g/cm³
Solubility in water Soluble in water
log P -3.13
Vapor pressure <0.01 mmHg (20°C)
Acidity (pKa) 12.5
Basicity (pKb) pKb = 3.5
Refractive index (nD) 1.462
Viscosity 20-35 cps
Dipole moment 6.72 D
Pharmacology
ATC code V03AB37
Hazards
Main hazards Harmful if swallowed. Causes severe skin burns and eye damage. May cause respiratory irritation.
GHS labelling GHS05, GHS07
Pictograms GHS05,GHS07
Signal word Danger
Hazard statements Harmful if swallowed. Causes severe skin burns and eye damage. Toxic to aquatic life with long lasting effects.
Precautionary statements P264, P280, P305+P351+P338, P337+P313
NFPA 704 (fire diamond) 2-0-0
Lethal dose or concentration LD50 (oral, rat) > 2000 mg/kg
LD50 (median dose) LD50 (median dose) = 570 mg/kg
NIOSH Not Listed
PEL (Permissible) Not established.
REL (Recommended) 200 mg/kg bw/day
IDLH (Immediate danger) Not Established
Related compounds
Related compounds Polyhexamethylene biguanide (PHMB)
Polyhexamethylene guanidine (PHMG)
Polyallylguanidine hydrochloride
Polymeric guanidine
Dodecylguanidine hydrochloride