Material Safety Data Sheet: Policresulen Impurity 5 Ammonium Salt (M-Cresol-4-Sulfonic Acid Ammonium Salt)

Identification

Product Name: Policresulen Impurity 5 Ammonium Salt
Chemical Name: M-Cresol-4-Sulfonic Acid Ammonium Salt
Synonyms: Ammonium 4-hydroxy-3-methylbenzenesulfonate
Recommended Use: Laboratory reagent, pharmaceutical intermediate
Manufacturer Details: Chemical supplier or manufacturing site information
Emergency Phone Number: National Poison Control Center, local emergency services

Hazard Identification

GHS Classification: Causes skin irritation, serious eye damage, respiratory tract irritation, hazardous to aquatic life
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, can cause skin irritation, may be harmful if inhaled, toxic to aquatic organisms
Pictograms: Corrosive, exclamation mark, environment
Precautionary Statements: Avoid breathing dust or fumes, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, avoid release to the environment

Composition / Information on Ingredients

Chemical Identity: M-Cresol-4-Sulfonic Acid Ammonium Salt
Molecular Formula: C7H9NO4S
Molecular Weight: 203.22 g/mol
Component: M-Cresol-4-Sulfonic Acid Ammonium Salt, 98-100%

First Aid Measures

General Advice: Move exposed individual away from area of exposure as quickly as possible, seek medical attention if symptoms develop
Inhalation: Move to fresh air, keep person comfortable, call poison control if there is coughing, wheezing, or chest tightness
Skin Contact: Immediately remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek immediate medical care if irritation persists
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, seek medical attention

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Specific Hazards: Thermal decomposition releases toxic gases like sulfur oxides, nitrogen oxides
Special Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Isolate area, prevent run-off from entering drains, keep cool containers exposed to flames with water spray, fight fire from a safe distance

Accidental Release Measures

Personal Precautions: Wear personal protective equipment including gloves, goggles, and respirator as needed
Environmental Precautions: Prevent spillage from entering waterways or drains, avoid soil contamination
Clean-up Methods: Absorb spill with inert material like sand, place in chemical waste container, ventilate area, wash spill site after material pickup
Disposal: Collect and dispose of waste following official regulations, prevent further leakage if safe to do so

Handling and Storage

Safe Handling: Use with adequate ventilation, avoid inhaling dust or fumes, avoid contact with skin, eyes, and clothing, keep away from food and beverages
Storage Conditions: Store in tightly closed, labeled containers, keep in a cool, dry, well-ventilated space, avoid extremes of temperature, keep away from incompatible substances such as strong acids or bases
Incompatibilities: Strong oxidizers, strong acids and bases, reducing agents

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation or chemical fume hood to minimize exposure
Eye Protection: Chemical safety goggles, face shield as needed
Hand Protection: Suitable chemical-resistant gloves such as those made from nitrile rubber
Body Protection: Wear laboratory coat or chemical apron
Respiratory Protection: Use approved respirator if ventilation is inadequate
Hygiene Measures: Wash hands, forearms and face after handling, remove contaminated clothing and wash before reuse

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Faint characteristic odor
Odor Threshold: Not determined
pH: 4.5-6.5 (1% in water)
Melting Point / Freezing Point: 210-215°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Not flammable under standard conditions
Evaporation Rate: Not volatile
Flammability (solid, gas): Not classified as flammable
Vapor Pressure: Negligible
Solubility: Soluble in water
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Decomposes above 200°C
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: Not expected under normal use
Conditions to Avoid: Excessive heat, open flames, incompatible materials
Incompatible Materials: Strong oxidizers, acids, bases, reducing agents
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide

Toxicological Information

Acute Toxicity: Data limited, may cause irritation if swallowed or in contact with skin or eyes
Skin Corrosion/Irritation: Causes skin irritation, repeated exposure may result in dermatitis
Serious Eye Damage/Eye Irritation: Causes serious eye irritation, may cause damage with direct contact
Respiratory Sensitization: May cause irritation of the respiratory tract with inhalation of dust
Carcinogenicity: No components listed as carcinogens by IARC, NTP, OSHA
Reproductive Toxicity: Insufficient data to conclude
Specific Target Organ Toxicity – Single Exposure: May cause respiratory irritation
Specific Target Organ Toxicity – Repeated Exposure: Not classified

Ecological Information

Aquatic Toxicity: Harmful to aquatic organisms, may cause adverse effects on aquatic environments with improper disposal
Persistence and Degradability: Data not fully available, aromatic sulfonic acids tend to persist in the environment
Bioaccumulative Potential: Bioaccumulation not expected based on available information
Mobility in Soil: Water soluble, may leach to groundwater if released in significant quantities
Other Adverse Effects: Avoid dispersal or release to the environment

Disposal Considerations

Product Disposal: Dispose of waste in accordance with local, state, national, and international regulations, avoid discharge to surface water or drains
Contaminated Packaging: Clean containers before disposal or recycle as per local policies, punctured or damaged containers may hold residue risks
Special Precautions: Handle contaminated materials using PPE, follow chemical waste procedures

Transport Information

UN Number: Not classified as hazardous under most dangerous goods regulations
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Marine Pollutant: Harmful to aquatic life, consider local rules
Special Precautions: Secure packaging to prevent spillage, ship under ambient conditions

Regulatory Information

Safety, Health and Environmental Regulations: Not classified as hazardous under GHS; not listed under major chemical inventories (TSCA, REACH) in significant quantities
TSCA Status: Not specifically listed
DSL/NDSL (Canada): Information not available
REACH Status (EU): Register as needed for production/import; safety data should accompany any commercial transaction
SARA Title III: Not listed
Other Local Regulation: Follow national regulations for handling and disposal, SDS access required for workplace safety