Long before chemists understood much about molecular manipulation, researchers noticed that guanidine itself carried unusual properties. It wasn’t long before experiments emerged where guanidine would be teamed up with different organic groups in search of new reactivity and better performance across industrial settings. Phenyl guanidine carbonate rose from this era, riding on the back of demand in pharmaceuticals, dyes, and specialty chemicals. As laboratories matured into more organized production facilities, the focus shifted from basic research toward batch consistency and application reliability.
Phenyl guanidine carbonate lands in a sweet spot for those aiming to modify molecular behavior without unnecessary complexity. In plain terms, it serves as a core reagent, especially in sectors where precision and predictable chemical profiles are required. Researchers turn to it for its controlled reactivity and solubility traits, while manufacturers value how it slots easily into chemical syntheses without regular complaints of instability or impurity. Most find it as a white to off-white powder, free-flowing, with a sharp but manageable odor profile.
With a melting point settled comfortably above room temperature, phenyl guanidine carbonate brings a certain stability to storage and transportation. Its molecular structure, a combination of a guanidine group bonded to a phenyl ring and coupled with the balancing force from carbonate, gives the compound the punch required for more specific chemical reactions. Its solubility in water and some alcohols paves the way for broad laboratory use, while low volatility reduces risks tied to inadvertent inhalation or explosions in tightly regulated environments. The molecule resists decomposition under normal ambient conditions, which not only simplifies shipping and long-term storage but also means users get a consistent product batch after batch.
Anyone who has set foot in an academic or industrial chemistry stockroom will recognize the importance of clear product specs and robust labeling. For phenyl guanidine carbonate, details matter—purity ranges, moisture content, and potential trace impurities find their way onto every bottle or drum. Manufacturers specify content by weight, with certificates tying purity levels to analytic standards favored by regulatory bodies or clients. Labels, often bearing hazard warnings in line with GHS or local standards, make clear the precautions: chemical burn risk, environmental care instructions, and required PPE for handling make up the heart of a responsible product packaging.
Synthesizing phenyl guanidine carbonate usually means starting with aniline or its derivatives and running it through guanidination reactions—fancy word, simple principle: attach a guanidine group to the phenyl core. The resulting compound then reacts with carbonate sources under set temperature and solvent controls. Later purification steps—solvent extraction, crystallization, and drying—separate the product from byproducts and unreacted feedstock. This multistep process draws from established industrial chemistry traditions, where equipment cleaning, process monitoring, and traceability play roles as vital as chemical reactivity. Each step hinges on minimum waste production, high yields, and manageable safety risks.
Phenyl guanidine carbonate doesn’t just sit on a shelf—it acts as a starting material in further syntheses, stepping forward in reactions where its basic group can attack acids or coordinate with metal ions. Its carbonate group, too, lends itself to modification. In pharmaceutical labs, it pairs with substrates to generate bioactive molecules, passing through steps like alkylation, acylation, and cyclization. Dyes and pigments benefit from the compound’s reactivity with various aromatic and heterocyclic reagents. Each transformation relies heavily on the product’s baseline purity and the predictable character of its chemical bonds.
Scientists and buyers encounter phenyl guanidine carbonate under several street names: N-phenylguanidinium carbonate, Benzylguanidine carbonate, or even just Phenylbiguanide carbonate in some catalogs. The cataloguing systems might change based on the supplier, country, or end market, but the core compound remains the same. In the rush of daily lab work, recognizing these alternate monikers prevents errors, especially when cross-referencing stock inventory lists or purchasing across borders, where translation or nomenclature practices diverge.
As any seasoned lab hand knows, the potential for cuts, burns, and toxic exposures sits around every corner. Phenyl guanidine carbonate, while more stable than some other reactive agents, demands practical care during handling. Storage involves sealed containers, cool and dry bins, and away from acids or strong oxidizers. Protective gear—gloves, goggles, and chemical-resistant coats—are non-negotiable, not just for those mixing in bulk but also for quick weighing or transfers. Emergency instructions call for thorough rinsing with water and immediate medical attention if skin or eye contact occurs. Disposal plans align with local regulations, often calling for incineration or secure landfill protocols to prevent accidental contamination.
The direct markets for phenyl guanidine carbonate span drug discovery labs, pigment industries, agricultural chemical synthesis, and even advanced material research hubs. Medicinal chemists put it to work crafting new therapeutic molecules, especially those aiming to target enzyme receptors or disrupt specific metabolic pathways. In dyes, the compound shapes the synthesis of stable coloring agents—those that stick to fabric or paper through many washes without losing vibrance. Agrochemical innovators test it as a building block in plant-protection molecules, betting on its power to tweak properties for greater crop safety or pest resistance. Materials scientists take a more experimental path, embedding the compound or its derivatives into polymers and coatings for unique mechanical or thermal properties.
Inside research organizations, phenyl guanidine carbonate draws the attention of those seeking new routes for carbon-nitrogen bond formation and molecular customization. Papers pop up each year, proposing next-generation synthetic pathways or exploring untapped reactivity through catalysts and green chemistry tweaks. University labs and startup ventures look for ways to extend the molecule’s reach, trialing it as a source of new functional materials or linking it to nanostructure growth for better energy harvesting. Funding from industry and government feeds this cycle, anchoring the compound in a steady stream of grant proposals and patent filings.
No rational scientist skips the safety data. Toxicological studies around phenyl guanidine carbonate typically circle around acute exposure tests, chronic impact assessments, and cell culture experiments searching for cytotoxic or mutagenic effects. Many of these studies point out that, at high doses or with repeated exposure, risks to organ function or cellular integrity rise, though routine lab use with PPE keeps these dangers in check. Environmental agencies increasingly demand thorough breakdown pathways and set discharge limits, especially where runoffs could crunch aquatic or soil microbiota. Over the last decade, animal testing has shifted toward more in vitro modeling, aiming to map out molecular-level effects before large-scale production approvals.
The next chapter for phenyl guanidine carbonate looks packed with opportunity as the hunt continues for more efficient, cleaner, and safer chemical reagents. Regulatory shifts toward sustainability and transparency drive innovation in synthesis and application. Digitalization in laboratories, from AI-driven optimization to blockchain traceability, stokes demand for compounds with reliable historic data and robust supply chain audits. Novel pharmaceutical scaffolds and materials science innovations rely on ever more selective reagents, with phenyl guanidine carbonate taking its place as both a proven performer and a springboard for future discovery. Training tomorrow’s chemists to understand its full capability and risk profile remains essential, as every advancement in laboratory or factory comes tethered to responsible practice and deep scientific understanding.
Phenyl guanidine carbonate doesn’t show up in daily conversation, but it plays an important part in both research and manufacturing. In my time working with laboratory professionals, I’ve seen this compound pop up whenever someone wants a specific chemical reaction or a new product. The backbone of phenyl guanidine carbonate is its strong basic nature and ability to interact with different molecules. That means researchers often use it to build more complex organic compounds, and pharmaceutical makers look at it for its consistent results when preparing new ingredients.
Building blocks matter a lot in drug development. In the pharmaceutical space, phenyl guanidine carbonate steps up as a key intermediate. Researchers choose it because it reacts predictably, making it easier to create new medicines. Its value isn’t just about reliability. This compound is part of the route to antiviral drugs and some anti-cancer agents. The fact that it can speed up the preparation of difficult molecules can shave weeks or months off projects that might otherwise crawl along. Time saved here means a shorter wait for patients who need treatment.
In academic and industrial labs, phenyl guanidine carbonate also enables certain detection routines. I remember sitting in on research meetings where scientists discussed using it for analyzing chemical fingerprints. It helps tweak molecular structures, so they light up under specialized analysis. These techniques matter in food safety checks and forensic investigations. Whenever there’s a question about the purity or identity of a substance, having stable reagents like this one instills confidence in the results.
Development in the agrochemical world draws heavily from pharmaceutical approaches. Companies investigating new ways to protect crops use phenyl guanidine carbonate to build novel molecules that can fend off pests or increase yields. There’s a lot of pressure on agriculture to keep up with population growth, and that means modernizing the chemistry behind fertilizers and pesticides. When I toured an agrochemical plant, I saw rows of reactor vessels running test batches that depended on specialty reagents like phenyl guanidine carbonate. These workers don’t see the end product, but their attention to each step in the chain ripples out to fields around the world.
Using specialty chemicals always brings a safety conversation to the table. Phenyl guanidine carbonate isn’t something to handle without proper training and gear. On my own lab tours, I saw glove boxes and fume hoods designed to keep workers safe. Companies committed to safety follow global standards for storage and disposal, so environmental risks remain low. Product data sheets from established suppliers spell out clear handling requirements, and responsible firms don’t cut corners. This approach not only protects people and the environment but also assures buyers that supply chains stand up to scrutiny.
Modern manufacturing and research expect clear information and reliable results. Suppliers who provide full documentation and quality assurances help research move forward. Using phenyl guanidine carbonate brings together technical skill and regulatory discipline. The more the scientific community talks openly about best practices and sourcing, the stronger future discoveries become. This collaboration matters whether the goal is a new cancer drug, safer crops, or breakthroughs in molecular science.
Chemistry isn't just for white coats and labs. Sometimes a compound crosses into everyday products or research tools, and it’s handy to know what’s inside. Phenyl guanidine carbonate is one of those specialized chemicals. You see it referenced in research documents, lab catalogs, and some pharmaceutical contexts. Its chemical backbone tells a story about how small molecular tweaks can affect all kinds of reactions or interactions.
To detail it simply, phenyl guanidine carbonate's formula spells out its structure: C8H11N3O3. Let’s break that out further. The “phenyl” means there’s a benzene ring, known for its ring of six carbons and hydrogens arranged in a tight, symmetric shape. That’s a familiar anchor in organic chemistry. The guanidine group stacks on with three nitrogens, typically contributing strong basicity. Then, carbonate rounds out the compound, bringing in a touch of CO3, which acts as a balancing counterion in many salts.
Ask any chemist why molecular weight matters, and plenty of answers pop up. It determines how you measure out substances, impacts how compounds dissolve, and helps with calculations for reactions. For phenyl guanidine carbonate, the molecular weight stands at 197.19 g/mol. This number means labs and manufacturers can weigh out the right amount with accuracy, vital for both small-scale research and bigger industrial tasks.
Knowing the formula and molecular weight isn’t just a box to check on a safety sheet. Let’s say a lab is looking to build new pharmaceutical candidates. Researchers rely on these basics to run experiments and ensure each test batch matches expectations. When I ran reactions in a university setting, mismatched weights or incorrectly copied formulas threw off entire days of work. This isn’t about abstract lab safety; it’s about practicality—every milligram, every decimal matters.
Outside the lab, regulatory agencies keep a close watch on chemical specifics. These details ensure substances meet safety requirements for handling, storage, and shipping. It’s no mystery why regulatory bodies push for transparency—mishandling chemicals with incorrect weights or formulas can escalate into safety risks or regulatory run-ins.
Mislabeling and mix-ups can happen. Suppliers occasionally list different hydrate forms or related salts, and all of a sudden, a reaction result makes no sense. Staying vigilant about double-checking the formula and verifying certificate of analysis from suppliers heads off trouble. It’s true, sometimes chemistry feels repetitive, but inaccuracy easily costs time and money down the road. Proper storage, standardized labeling, and clear record-keeping prevent these headaches from showing up in the first place.
Open access to reliable chemical data isn’t a luxury — it provides a foundation for researchers, regulators, and end users. Leveraging digital tools to confirm formulas and check recent molecular weights can save hours otherwise lost to cleanup. Building close relationships with trusted suppliers helps resolve ambiguities, especially for chemicals like phenyl guanidine carbonate that aren’t as widely known as the more common industrial salts.
Staying rooted in simple, clear details goes far in science or industry. With the right numbers in hand, decisions turn sharper, risks drop, and work gets done right the first time.
Phenyl guanidine carbonate plays a role in many chemical processes—from labs in universities to manufacturing industries. Its powdery, odorless appearance might not look threatening, but storing it safely teaches crucial lessons about respect for chemicals. Anyone who has handled it knows that a handful of careless choices can put both workers and research projects at risk.
Leaving containers open or ignoring storage rules leads to more than just lost samples. Phenyl guanidine carbonate reacts with moisture in the air. I’ve seen labs lose months of work after containers got left open overnight, and the compound clumped together. Even small amounts of water trigger changes in the substance, turning a precise experiment into a guessing game. Safety risks rise as well—a powder that’s stable in the right bottle becomes a hazard if exposed to the wrong environment.
Every lab worker should treat temperature and humidity as daily watchwords. Phenyl guanidine carbonate stores best at room temperature—between 20 and 25 degrees Celsius—and always in a dry place. Heat speeds up unwanted reactions. I remember an assistant who stored chemicals near a sunny window. A week later, not only was the material ruined, but the plastic jar warped. Cooler, shaded places make a world of difference.
Glass and hard plastics with tight-sealing lids work best. Screw caps beat snap-on types every time. I stay clear of thin bags or flimsy vials. Proper labeling helps everyone on the team keep track of what’s inside, and clear hazard markings alert new staff to handle the container with care. A label showing the date and initials also reminds staff to rotate stock, using older materials first.
Storage rooms become safer with shelves above ground level—far from spilled water, cleaning buckets, or overhead leaks. I once worked at a plant that stored chemicals under a leaky sink. It took just one accident for the maintenance team to move every container onto solid, elevated racks. Fire safety rounds out the picture. Chemicals stored near heat sources, radiators, or electrical panels ask for trouble. Distance keeps everyone safer.
Good storage goes hand-in-hand with good habits. Disposable gloves stop skin contact each time the bottle opens. Consulting the safety data sheet for phenyl guanidine carbonate delivers more than legal compliance—it spells out real dangers and daily precautions in plain language. Shared logs for weekly inspections encourage accountability on every shift. If signs of dampness or clumping show up, it’s time to dispose of the batch safely and check on the storage setup.
Stories from experienced chemists point to investing in climate-controlled cabinets and automating inventory tracking. New workers benefit when veterans walk them through the steps rather than dumping dense manuals on their desks. Solid teamwork, good recordkeeping, and prompt disposal of compromised material keep both people and projects safe in every setting handling phenyl guanidine carbonate.
Few topics trigger quite as much worry as chemical safety in the workplace. Over the years, I’ve seen how even ordinary lab routines demand trust in proper information about each compound around us. So, a question about phenyl guanidine carbonate pulls me in — real lives, not just regulations, are at stake with any substance carelessly managed on a shelf or spilled at a workbench.
Phenyl guanidine carbonate is a solid white compound that handlers often encounter in research and certain industrial work. This chemical doesn’t show up on consumer shelves, but students, technicians, and scientists bump into it behind the scenes. The safety information assigned to it flags irritation risks with exposure through eye, skin, or inhalation routes. It’s not just about discomfort. Inhaled dust stirs headaches and sickness; direct skin contact might trigger redness or rashes. Accidental splashes in the eye hurt, and swallowing this compound won’t go down lightly, either.
Nobody has to look hard for alarming stories about underestimating chemical dust or improper container labeling. It only takes a single lapse: A worker brushes powder from a tabletop and develops a rash. Someone leans in to sniff, curious, and coughs for an hour. This isn’t theoretical. Respecting the hazard comes from experience, not rulebooks.
Every chemical with irritant traits deserves careful treatment. This starts with gloves that won’t let powder seep through, protective eyewear that sits tight, and a lab coat that goes right into the laundry at day’s end. Proper ventilation cuts down on fumes and dust in the air; nobody wants to breathe particles if a spill occurs. In shared spaces, a disposable dust mask or a respirator makes good sense. Any open container should stay capped when not in immediate use.
A reliable chemical label matters more than an extra layer of bureaucracy. Mistakes don’t begin with huge errors — they begin with sloppy habits. The habit of keeping things labeled, cleaning up right away, and storing chemicals in sturdy cabinets where only trained eyes wander keeps whole teams safe.
Even the best system sometimes fails. Fast action is possible only with honest training and frequent drills. Spilled phenyl guanidine carbonate on the skin means rinsing under water, not just wiping off. Eyes demand a flush at the eyewash station. Breathing trouble calls for open air, not just bravado. A colleague may need to know which chemical they have encountered, so having printed safety data sheets nearby pays off.
Many labs post clear steps for cleanup, including specific bins for chemical waste. Tossing contaminated materials in general trash turns a local problem into a wider one. Good practice means segregating waste and knowing who handles final disposal.
There’s no substitute for respect. Each bottle brings its own story. Colleagues who treat phenyl guanidine carbonate with care rarely run into trouble; those who treat it like baking soda do not stay lucky for long. Training, vigilance, and clear protocols — these are the real shields against mishap, not wishful thinking or shortcuts.
Working in a lab often means trouble if your starting materials fall short. Purity plays a massive role, not just in the quality of final products, but also for safety and compliance. Phenyl guanidine carbonate acts as a building block in several chemical syntheses. Even the tiniest impurities may cause unpredictable outcomes that turn promising experiments into wasted time.
Take an industrial chemical that contains just 98% purity. That leftover 2% can turn up as unknown byproducts, which, in sensitive pharmaceuticals or specialty materials, can easily ruin a critical reaction. It’s tempting to cut corners for price, but impurities often come back to haunt you—unexpected colors, smells, inconsistent reaction yields, or even hazardous byproducts.
Phenyl guanidine carbonate typically arrives in grades such as technical, laboratory, and high-purity (sometimes labeled as analytical grade). Technical grade leans more toward uses where cost trumps performance: think bulk industrial processes, where a small impurity load might not matter much. Laboratory grade strikes a balance, good enough for research but not always dependable for regulated, high-stakes projects.
High-purity or analytical grade raises the bar, with purity often quoted above 99%. These batches pass stringent quality checks—measured by HPLC or mass spectrometry, with certificates to prove the absence of interfering chemicals. As a researcher, I learned early that even a 0.2% contaminant might twist the outcome. Skimping on grade means more failed runs, more troubleshooting.
A label or supplier catalogue isn’t enough. Suppliers sometimes rely on outdated specs, especially with intermediates like this one. Look for a certificate of analysis, not a generic datasheet. Good suppliers update their documentation batch by batch.
Ask for recent chromatograms if your work has tight specs. If you notice batch-to-batch variation, you’re not alone. Some labs have had to run separate verification on every order, just to make sure it matches promised purity. Reputable chemical providers also run heavy metal and moisture testing, guarding against hidden variables.
Certain industries watch these numbers closely. Pharmaceutical and agrochemical companies run routine tests to rule out any unknown or toxic compounds. Regulatory authorities, like the U.S. FDA or the European Medicines Agency, expect finished products to pass not just final tests, but also demand proof that all intermediates met particular purity standards.
Without strong purity controls, downstream problems pile up. Manufacturing lines may suffer shutdowns. Unanticipated health risks enter the mix for everyone handling the chemical. For researchers, using a low-grade chemical can mean re-running months of work.
If the plan involves fine chemicals, the safest strategy is to pick a trusted supplier and review each certificate of analysis personally. Cross-check batch numbers, use supporting data like melting points, and confirm that packaging prevents contamination during transit.
Price always tempts, but past mistakes have shown how saving a few dollars can balloon costs through failed batches and downtime. In this business, prioritizing purity from the start pays off—not only for the science, but for everyone’s safety and peace of mind.
| Names | |
| Preferred IUPAC name | phenylguanidine;carbonic acid |
| Other names |
Guanidine carbonate Guanidinium carbonate Carbonic acid guanidine salt |
| Pronunciation | /ˈfiː.nɪl ɡwəˈnɪːdiːn ˈkɑː.bə.neɪt/ |
| Identifiers | |
| CAS Number | 593-85-1 |
| 3D model (JSmol) | `/AAACQRQAAAAAAAAAAAAAAAAAAAAAAADKXQAAAAAAQgAAAMpdx3GDFBgk0TKG6ZRLMQAAARAwUzRACMmExgk8zAAMQxgk2gBzAIIEkCBUAADMAIkEiQMTF8/AwZAYwJcAAAAAAS1QwGRwyRAAAAAA` |
| Beilstein Reference | 26437 |
| ChEBI | CHEBI:76210 |
| ChEMBL | CHEMBL127489 |
| ChemSpider | 14639113 |
| DrugBank | DB13637 |
| ECHA InfoCard | ECHA InfoCard: 100.123.065 |
| EC Number | 214-954-9 |
| Gmelin Reference | 86383 |
| KEGG | C18617 |
| MeSH | D010660 |
| PubChem CID | 137349183 |
| RTECS number | FF5950000 |
| UNII | 9GRV8ZC42K |
| UN number | UN2811 |
| Properties | |
| Chemical formula | C8H13N5O3 |
| Molar mass | 242.23 g/mol |
| Appearance | White crystalline powder |
| Odor | Odorless |
| Density | 0.81 g/cm³ |
| Solubility in water | Soluble in water |
| log P | -2.37 |
| Acidity (pKa) | 8.1 |
| Basicity (pKb) | 5.45 |
| Magnetic susceptibility (χ) | -47.5e-6 cm³/mol |
| Refractive index (nD) | 1.455 |
| Dipole moment | 3.48 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 321.6 J·mol⁻¹·K⁻¹ |
| Pharmacology | |
| ATC code | N06BX08 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes serious eye irritation. Causes skin irritation. May cause respiratory irritation. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07, GHS09 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. |
| Precautionary statements | P261, P280, P305+P351+P338, P337+P313 |
| Flash point | 175°C |
| Autoignition temperature | 225°C |
| Lethal dose or concentration | LD50 Oral Rat 3200 mg/kg |
| LD50 (median dose) | LD50 (median dose): 590 mg/kg (rat, oral) |
| NIOSH | JN8570000 |
| PEL (Permissible) | PEL: 15 mg/m³ |
| REL (Recommended) | 4°C |
| IDLH (Immediate danger) | Unknown |
| Related compounds | |
| Related compounds |
Phenylguanidine Guanidine carbonate Phenyl isothiocyanate Phenylhydrazine Phenyl urea |
