Name: O-Methylsalicylic Acid
Synonyms: 2-Methoxybenzoic Acid, Ortho-Methoxybenzoic Acid
Chemical Formula: C8H8O3
Molecular Weight: 152.15 g/mol
CAS Number: 118-90-1
Recommended Use: Laboratory chemical, synthesis of pharmaceuticals, specialty chemicals research
Supplier Information: Name, address, emergency phone number and email of chemical vendor/distributor
Classification: Eye irritation, skin irritation, specific target organ toxicity (single exposure, respiratory tract)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may harm respiratory system if dust inhaled
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, wash exposed skin after handling, wear protective gloves, protect eyes, take care to avoid static discharge
Potential Health Effects: Irritation to skin and respiratory system, risk of eye damage upon contact, possible headache or dizziness from inhalation exposure
Chemical Name: O-Methylsalicylic Acid
CAS Number: 118-90-1
Concentration: ≥ 98% pure as technical grade material
Impurities: Minimal, may include traces of related aromatic acids or solvent residues (full details from supplier COA)
Stabilizing Agents: No additional stabilizers or additives reported
Eye Contact: Rinse eyes under running water for at least 15 minutes, remove contact lenses if present, seek medical attention immediately
Skin Contact: Wash skin thoroughly with soap and plenty of water, remove contaminated clothing, consult doctor if irritation persists
Inhalation: Move person to fresh air, keep at rest, give oxygen if breathing is difficult, medical attention if symptoms develop
Ingestion: Rinse mouth, do not induce vomiting, drink water if alert, get medical advice without delay
Symptoms: Redness, itching, blurred vision, cough, sore throat, stomach upset in severe oral exposure
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray, use methods appropriate for materials stored nearby
Hazards from Combustion: Produces acrid smoke with carbon monoxide, carbon dioxide, and potentially undetermined combustion products
Protective Equipment: Full firefighting gear, self-contained breathing apparatus, avoid inhalation of smoke or fumes
Firefighting Instructions: Prevent runoff from entering drains or water supplies, cool sealed containers exposed to fire, evacuate area and fight fire from a safe distance
Reactivity with Fire: Dust can form explosive mixture with air under some conditions
Personal Protection: Wear gloves, protective clothing, safety goggles, dust mask or respirator rated for organic dusts
Spill Cleanup: Sweep up and place in chemical waste container, avoid raising dust, ventilate area, wash contaminated surfaces with water and mild detergent
Environmental Precautions: Prevent entry into waterways, sewers or confined spaces
Containment: Use barriers to control spread of spilled material, collect for proper disposal
Decontamination: Clean surfaces with water, ensure proper ventilation, dispose of wipes and cleaning materials as chemical waste
Safe Handling: Keep containers tightly closed, avoid inhalation and contact with eyes, skin, use in well-ventilated areas, handle empty containers as if contaminated
Storage Conditions: Keep in a dry, cool, well-ventilated location, away from incompatible materials, light, heat, avoid humidity
Incompatible Materials: Strong oxidizing agents, strong acids, alkalis, iron salts
Packaging Materials: Store in suitable chemical-resistant containers, label properly
Storage Precautions: Limit access to trained personnel, secure storage area, check containers regularly for leaks or damage
Exposure Limits: No strict occupational exposure limits established, exposure should be minimized using engineering controls
Engineering Controls: Fume hood, local exhaust, general area ventilation, dust collection equipment
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), lab coat, closed-toed shoes, safety goggles, dust respirator if airborne levels are high
Hygiene Measures: Wash hands after handling, do not eat, drink or smoke in the work area, handle in accordance with industrial hygiene standards
Monitoring: Regular checks of airborne concentration suggested in high-use settings
Appearance: White to off-white crystalline powder
Odor: Faint aromatic scent
Melting Point: 185–187 °C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, freely soluble in ethanol and ether
pH: Not readily available; acidic in solution
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.26 g/cm³
Partition Coefficient (log Kow): 1.85 (estimated)
Flash Point: Not determined but expected to be well above ambient temperature
Autoignition Temperature: Not available
Evaporation Rate: Negligible
Chemical Stability: Remains stable under normal conditions of storage and handling
Reactivity: Not prone to hazardous reactions with common laboratory reagents
Hazardous Reactions: Combines vigorously with strong oxidizers, can react with strong acid and base
Decomposition Products: Emits acrid smoke, carbon oxides upon significant heating or combustion
Conditions to Avoid: Excessive heat, open flame, strong light, moisture, incompatible chemicals
Polymerization: No polymerization hazard expected
Routes of Exposure: Eyes, skin, inhalation, ingestion
Acute Toxicity: Low acute toxicity, may cause irritation at point of contact, oral LD50 in rats > 2000 mg/kg
Chronic Effects: Repeated exposure may lead to dermatitis, respiratory sensitization
Skin Corrosion/Irritation: Causes skin irritation in animal models
Serious Eye Damage/Irritation: Eye irritation proven in rabbit assays
Respiratory or Skin Sensitization: Possible respiratory tract irritation, no evidence of skin sensitization
Germ Cell Mutagenicity / Carcinogenicity: Not classified as mutagenic or carcinogenic based on available data
Reproductive Toxicity: Not classified for reproductive toxicity
Target Organ Effects: Prolonged exposure may affect respiratory tract, skin
Ecotoxicity: Limited studies suggest low toxicity to aquatic organisms, but observed toxicity at high concentrations
Persistence and Degradability: Expected to degrade in the environment, breakdown via microbial action
Bioaccumulation Potential: Not likely to bioaccumulate based on log Kow value
Mobility in Soil: Slight mobility expected, does not persist in groundwater
Other Adverse Effects: Take care to prevent large releases to surface water, soil, or storm drains; effects on plants, aquatic life at excessive concentrations cannot be ruled out
Product Disposal: Dispose of as hazardous chemical waste in accordance with local, regional and national requirements
Packaging Disposal: Triple rinse and puncture empty containers before recycling or disposal, label as hazardous chemical containers
Recommended Disposal Methods: High-temperature incineration, follow local environmental agency regulations
Precautions: Avoid discharge to surface water or sewer
Disposal Prohibitions: Do not dispose of with regular municipal waste or down drains
UN Number: Not regulated for transport under UN Recommendations
Proper Shipping Name: Not classified as dangerous for transport by land, sea or air under ADR, IMDG, IATA
Packing Group: Not assigned
Transport Hazards: Not subject to special transport requirements, though care is warranted to avoid damage or leaks during transit
Special Precautions: Secure containers, avoid exposure to heat, store away from foodstuff and incompatible chemicals during transit
Environmental Hazards: Not a marine pollutant as per regulations, prevent accidental release
International Inventories: Listed on TSCA (US), EINECS/ELINCS (Europe), DSL (Canada), AICS (Australia), ENCS (Japan)
OSHA Status: Not specifically regulated as hazardous by OSHA, general chemical hygiene applies
SARA Title III Sections 302/313: Not listed
California Prop 65: Not on Prop 65 list of chemicals known to the state to cause cancer or reproductive harm
WHMIS (Canada): Classified as hazardous (irritant)
Other Regulations: Subject to chemical hazard communication standards, ensure proper hazard labeling and documentation are maintained at all sites handling the material
