Product Name: Guanidine Hydrochloride
Chemical Formula: CH5N3·HCl
CAS Number: 50-01-1
Recommended Use: Laboratory reagent, RNA and protein denaturant for medical and research purposes
Supplier Details: Manufacturer address, phone number, email contact for responsible party
Emergency Phone Number: Listed 24-hour medical emergency support line
GHS Classification: Acute oral toxicity (Category 3), Skin irritation (Category 2), Eye irritation (Category 2A)
Signal Word: Danger
Hazard Statements: Toxic if swallowed, causes skin and eye irritation
Pictograms: Skull and crossbones, exclamation mark
Precautionary Statements: Avoid breathing dust, wash hands thoroughly, wear gloves and eye protection
Chemical Name: Guanidine Hydrochloride
SYNONYMS: Guanidinium chloride, Aminoformamidine hydrochloride
CAS Number: 50-01-1
Concentration: Pure, >99% by weight
Impurities: None detected in analytical grade
Inhalation: Move affected person to fresh air, consult a physician if symptoms develop
Skin Contact: Wash area with plenty of water and soap for at least 15 minutes, remove contaminated clothing
Eye Contact: Rinse eyes cautiously with water for 15 minutes, seek immediate medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek medical treatment immediately
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Special Hazards: Hydrogen chloride, nitrogen oxides, and carbon oxides may form from thermal decomposition
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Advice for Firefighters: Prevent runoff from entering drains or waterways
Personal Precautions: Evacuate unnecessary personnel, use personal protective equipment, avoid dust formation
Environmental Precautions: Prevent release into drains and surface water, contain spill with suitable barriers
Cleanup Methods: Scoop up without creating dust, collect in suitable closed container for disposal, ventilate area
Handling: Use only in well-ventilated areas, avoid contact with skin and eyes, prevent ingestion and inhalation
Storage: Store in a tightly closed container, in a cool, dry, ventilated area, separate from incompatible substances such as strong oxidizers and acids
Hygiene Measures: Prohibit eating, drinking, and smoking in areas where product is handled, wash hands after use
Exposure Limits: No occupational exposure limits established, handle with care to minimize risks
Engineering Controls: Use fume hood or adequate exhaust ventilation
Personal Protective Equipment: Chemical-resistant gloves, lab coat, safety goggles, approved respirator for dust
Environmental Controls: Avoid environmental release, manage waste appropriately
Appearance: White crystalline powder
Odor: Odorless
Molecular Weight: 95.53 g/mol
Solubility: Soluble in water (2360 g/L at 20°C)
pH: 6.4 (1 mol/L solution)
Melting Point: 181–184°C (decomposes)
Boiling Point: Decomposes before boiling
Vapor Pressure: Not volatile
Flash Point: Not applicable
Partition Coefficient: Not determined
Chemical Stability: Stable under normal storage and handling conditions
Conditions to Avoid: Heat, humidity, moisture, incompatible materials, ignition sources
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Hydrogen chloride gas, nitrogen oxides
Polymerization: Will not occur
Route of Exposure: Can enter the body through inhalation, ingestion, skin, and eye contact
Acute Toxicity: LD50 (oral, rat): ~950 mg/kg
Skin Irritation: May cause redness and irritation
Eye Irritation: Causes irritation upon contact
Symptoms of Exposure: Nausea, headache, dizziness, skin and respiratory irritation
Chronic Effects: Long-term exposure may affect liver and kidney function, not listed as a carcinogen
Toxicity: Harmful to aquatic life with long lasting effects
Environmental Fate: Product is water soluble, may distribute into the aquatic environment
Persistence and Degradability: Not readily biodegradable
Bioaccumulation: Potential predicted to be low
Mobility in Soil: High solubility increases mobility in environmental compartments
Waste Treatment Methods: Dispose material as hazardous chemical waste using licensed facilities
Contaminated Packaging: Dispose of as unused product, triple rinse containers before recycling or disposal
Other Information: Do not dispose of in household refuse or sewage systems, compliance with local laws is required
UN Number: 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (Guanidine Hydrochloride)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Risks: Not a marine pollutant
Special Precautions: Secure packaging, accurate labeling, notification to carrier if shipped in large quantities
OSHA: Regulated hazardous material
TSCA: Listed in United States TSCA inventory
EC Regulation: Meets criteria under Regulation (EC) No 1272/2008
Other Regulations: Compliant with WHMIS, REACH pre-registered
Label Elements: Required signal words, hazard statements, pictograms on containers
