Product Name: Guanidine Phosphate
Chemical Formula: CH6N3O4P
Synonyms: Phosphoric acid guanidine salt, Guanidinium dihydrogen phosphate
Recommended Use: Flame retardant, industrial chemical, laboratory reagent
Manufacturer: Refer to packaging or supplier
Emergency Contact Number: Refer to label or safety officer
CAS Number: 5423-22-3
UN Number: 3077
EC Number: 226-506-3
Supplier Address: Listed on product label or invoice
Relevant Identified Uses: Intended for use in strictly controlled settings such as chemical research, flame proofing of textiles, and certain controlled industrial processes; not for general consumer use
Classification: Eye irritation, Skin irritation, Acute toxicity (oral), Aquatic hazard
Hazard Statements: Causes skin and eye irritation. May be harmful if swallowed. May be hazardous to aquatic life with prolonged effects.
Signal Word: Warning
Pictograms: Exclamation mark, Environment
Precautionary Statements: Avoid contact with skin and eyes. Do not breathe dust. Wear suitable protective equipment. Contain spills to prevent release into environment.
Other Hazards: Exposure to dust may worsen respiratory symptoms in sensitive individuals. Hygroscopic property may cause caking.
Chemical Name: Guanidine Phosphate
Concentration: 98–100%
Impurities: Trace amounts of related guanidine compounds, phosphates, and water
Additives: None reported
Formula: CH6N3O4P
Molecular Weight: 155.06 g/mol
General Advice: Remove affected persons from exposure, seek fresh air, and remove contaminated clothing. Give medical attention in all serious cases.
Inhalation: Move person to fresh air. If symptoms such as coughing or shortness of breath persist, seek medical aid.
Skin Contact: Wash off with plenty of water and soap. Remove contaminated clothing and wash before reuse. If irritation continues, consult a physician.
Eye Contact: Rinse cautiously with water for several minutes, lifting eyelids to ensure thorough rinsing. Remove contact lenses if present and continue rinsing.
Ingestion: Rinse mouth thoroughly with water. DO NOT induce vomiting. Give small amounts of water if person is conscious. Seek medical guidance.
Most Important Symptoms: Skin and eye irritation, possible mild respiratory discomfort, gastrointestinal upset after ingestion.
Note to Physician: Treat symptomatically based on clinical presentation.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide—do not use water jets directly.
Hazards from Combustion: Decomposition releases nitrogen oxides, phosphorus oxides, and possibly cyanide-containing vapors, which pose a toxic hazard.
Protective Actions: Firefighters require full protective gear including self-contained breathing apparatus to guard against fumes.
Fire and Explosion Risks: Product is nonflammable but may give off irritant or toxic fumes under fire conditions.
Special Equipment: Use equipment resistant to chemical corrosion and heat.
Additional Instructions: Dike and contain water runoff. Cool containers exposed to fire with water spray.
Personal Precautions: Avoid generating dust, wear respiratory protection (P2 or N95 mask), gloves, safety goggles, and protective clothing.
Environmental Precautions: Prevent entry to waterways, drains, confined areas, and soil. Notify relevant environmental authorities if significant release is likely to affect groundwater or surface water.
Cleanup Methods: Use spark-proof tools and non-metallic shovels. Sweep or vacuum up slowly to minimize dust. Place in properly labeled containers for re-use or disposal. Wash spill area with water after removal.
Other Recommendations: Dispose of contaminated cleanup materials as hazardous waste. Clean thoroughly before reuse of spill gear.
Handling Procedures: Avoid inhalation, ingestion, and contact with skin or eyes. Minimize dust generation. Handle in a ventilated area with adequate exhaust systems.
Technical Measures: Use only with proper engineering controls such as local exhaust ventilation.
Conditions for Safe Storage: Store in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials—especially oxidizers, acids, and bases.
Incompatibilities: Strong acids and oxidizing agents; such reactions may cause thermal decomposition or violent release of gases.
Storage Temperatures: Below 25°C advised, away from moisture since product is hygroscopic.
Specific End Uses: Only use for laboratory research, industrial flame-retardant or approved applications, never in food or medication.
Engineering Controls: Local exhaust ventilation. Process enclosures whenever feasible. Safety showers and eye wash stations in work area.
Exposure Limits: No OSHA or ACGIH exposure limit for guanidine phosphate, but keep dust below general nuisance particulate limits (<10 mg/m³, total dust).
Respiratory Protection: Use a particulate respirator (N95 or equivalent) when dust is generated or in closed environments.
Eye Protection: Chemical safety goggles or face shield.
Skin Protection: Nitrile or PVC gloves, long-sleeved clothing, laboratory coat.
Hygiene Measures: Wash hands thoroughly after handling. Use no eating, drinking, or smoking during work.
Environmental Controls: Prevent further spread in case of large spill; use closed systems if possible.
Appearance: White crystalline powder
Odor: Odorless
pH (1% Solution): 4.5–5.5
Melting Point: >200°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Soluble in water, slight solubility in alcohol
Density: ~1.58 g/cm³
Flash Point: Not flammable
Vapor Pressure: Not relevant (solid at room temperature)
Partition Coefficient (n-octanol/water): Not available
Evaporation Rate: Not applicable
Explosive Properties: Not explosive
Oxidizing Properties: Not oxidizing
Decomposition Temperature: >200°C (phosphorus and nitrogen compounds released)
Chemical Stability: Stable under normal ambient and anticipated storage and handling conditions.
Conditions to Avoid: Exposure to moisture, elevated temperatures, incompatible substances.
Incompatible Materials: Strong acids and oxidizers. Reactions may lead to thermal decomposition, releasing ammonia, nitrogen oxides, or toxic gases.
Hazardous Decomposition Products: Ammonia, nitrogen oxides, phosphorus oxides, cyanide compounds (in fire)
Reactivity: Relevant only in the presence of strong acids or bases.
Polymerization: Hazardous polymerization does not occur.
Acute Toxicity (oral): LD50 (rat): 2600–3500 mg/kg
Acute Toxicity (dermal): Data limited; low toxicity expected by analogy
Acute Toxicity (inhalation): May cause mild irritation to respiratory tract
Skin Corrosion/Irritation: Causes moderate irritation, particularly with prolonged exposure
Eye Damage/Irritation: Causes notable irritation with redness, tearing, possible injury on direct contact
Sensitization: No data on sensitization in humans or animals
Carcinogenicity: No classification by IARC, NTP, or OSHA; insufficient data
Mutagenicity: No significant mutagenic effects noted in standard bacterial or mammalian systems
Reproductive Toxicity: No conclusive evidence available
Repeated Dose Toxicity: Not established, use caution
Ecotoxicity: Aquatic studies suggest potential hazard to aquatic organisms especially in prolonged exposure scenarios; LC50 fish (96h): >100 mg/L
Persistence and Degradability: Inorganic phosphate likely persists in environment, guanidine moiety may degrade slowly
Bioaccumulative Potential: Neither component shows significant bioaccumulation potential
Mobility in Soil: Highly soluble in water, likely to leach into groundwater if released in significant quantities
Other Adverse Effects: May contribute to eutrophication if released in large quantities to aquatic environments. Avoid uncontrolled discharge to environment
Disposal Methods: Dispose of waste through licensed waste disposal contractor. Dilute aqueous solutions with plenty of water before draining; solids go to chemical waste landfill or incinerator. Follow local, state, and federal disposal regulations.
Contaminated Packaging: Empty containers retain product residue—treat as hazardous. Rinse thoroughly before recycling if allowed.
Special Precautions: Do not allow significant quantities into surface waters, sewers or soil. Never dispose with household waste or general waste streams.
UN Number: 3077
UN Proper Shipping Name: Environmentally Hazardous Substance, Solid, N.O.S. (contains Guanidine Phosphate)
Transport Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Environmental Hazards: Classified as environmentally hazardous material under IMDG and ADR
Special Precautions: Protect containers from physical damage. Avoid moisture ingress during transport. Ensure labeling and documentation in compliance with international and local transport regulations.
Bulk Transport: Not intended for bulk shipment except by licensed handlers
US TSCA: Listed
EU REACH: Exempted as an inorganic compound but may require registration if used in significant quantities
GHS Classification: Eye irritant, acute oral toxicity, aquatic chronic hazard
Other International Inventories: Check with local chemical registries
Workplace Regulations: Subject to OSHA, WHMIS, and other worker protection standards for chemical handling and exposure limits
Labeling: Hazardous symbol and precautionary statements per GHS standards required on all packaging and containers
Factory and Storage Rules: Must comply with local fire codes, hazardous materials storage guidelines, lab safety protocols, and staff training requirements
