MSDS for Aniline-2-Sulfonic Acid, 95%

Identification

Product Name: Aniline-2-Sulfonic Acid, 95%
Chemical Formula: C6H7NO3S
Synonyms: o-Aminobenzenesulfonic acid, 2-Aminobenzenesulfonic acid
CAS Number: 88-21-1
EC Number: 201-812-4
Supplier Details: Chemical supplier contact information, emergency phone numbers for chemical emergencies
Recommended Uses: Intermediate for dye synthesis, laboratory reagent
Restrictions on Use: Avoid use outside professional laboratory or industrial settings

Hazard Identification

GHS Classification: Acute Toxicity (oral, dermal), Skin Irritant, Eye Irritant, Specific Organ Toxicity, Environmental Hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled, causes skin and eye irritation, may cause respiratory irritation, suspected of damaging fertility, toxic to aquatic life
Pictograms: Exclamation mark, Health Hazard, Environment
Precautionary Statements: Wash thoroughly after handling, avoid release into environment, wear protective gear, use only outdoors or in a well-ventilated area, do not eat, drink, or smoke during use
Routes of Entry: Inhalation, ingestion, skin and eye contact
Target Organs: Kidneys, liver, blood, respiratory tract

Composition / Information on Ingredients

Chemical Name: Aniline-2-Sulfonic Acid
Concentration: 95%
Impurities: Unreacted aniline, related sulfonic acid isomers, trace inorganic salts
Molecular Weight: 173.19 g/mol
Hazardous Ingredients: Aniline-2-Sulfonic Acid (main component), possible minor fractions of hazardous organic derivatives

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy to do, continue rinsing, seek medical attention immediately
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water and soap, seek medical assistance if irritation continues
Inhalation: Remove person to fresh air, keep at rest in position comfortable for breathing, seek medical attention for persistent symptoms
Ingestion: Rinse mouth thoroughly, do not induce vomiting, never give anything by mouth to an unconscious person, seek immediate medical help
Most Important Symptoms: Irritation, redness, coughing, nausea, dizziness
Notes for Physician: Treat symptomatically, monitor for signs of methemoglobinemia in severe exposures

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Media: Avoid direct water jet on leaking material to prevent chemical dispersion
Specific Hazards: Releases toxic gases under combustion including nitrogen oxides and sulfur oxides
Protective Equipment: Wear full fire-fighting turnout gear, self-contained breathing apparatus
Special Procedures: Move containers from fire area if it can be done safely, cool containers with water spray to prevent rupture, avoid inhalation of combustion fumes

Accidental Release Measures

Personal Precautions: Wear protective clothing, chemical splash goggles, appropriate gloves, avoid breathing dust or vapors
Environmental Precautions: Prevent entry into waterways, drains, or soil; report releases as required by local regulations
Containment Methods: Sweep up spills, avoid creating dust, transfer to labeled containers for disposal, ventilate area
Cleaning Procedures: Wash spill site thoroughly after material pick-up is complete, use absorbent materials for small liquid spills, large spills require evacuation and containment by trained personnel
Decontamination: Dispose contaminated cleaning materials as hazardous waste

Handling and Storage

Handling: Use chemical fume hood or adequate ventilation, avoid all forms of contact, the product can stain skin and cause irritation, wash hands immediately after handling
Hygiene Practices: Remove contaminated clothing and wash before reuse, keep food and drinks away from work area
Storage Conditions: Store in tightly closed containers, away from heat, moisture, incompatible substances like strong oxidizers, acids or bases
Temperature Control: Do not expose to extreme heat
Packaging materials: Use corrosion-resistant containers such as polyethylene or glass lined steel

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA/ACGIH exposure limits for Aniline-2-Sulfonic Acid, maintain exposure as low as reasonably achievable
Engineering Controls: Mechanical exhaust, eye wash stations, safety showers in work area, closed system operation when possible
Respiratory Protection: Use approved respirators when dust, mist, or fumes are present
Hand Protection: Chemical-resistant gloves made from nitrile or neoprene, frequent replacement recommended
Eye Protection: Safety goggles or face shield
Skin Protection: Chemical-resistant protective clothing such as lab coat, apron
Hygiene Measures: Strictly prohibit food and drink in chemical area, wash thoroughly after handling material
Environmental Controls: Minimize release to environment, use containment systems to trap spills or leaks

Physical and Chemical Properties

Appearance: Gray to brownish crystalline powder
Odor: Slight aromatic odor
Odor Threshold: Not established
pH: 2.1 (1% solution in water)
Melting Point: 245-250°C (decomposes)
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not volatile
Flammability: Not considered flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Density: 1.59 g/cm³
Solubility: Soluble in water, limited solubility in ethanol, insoluble in ether
Partition Coefficient: Not determined
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Decomposes above 245°C
Viscosity: Solid, not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Can react with oxidizing agents, forming hazardous products
Hazardous Reactions: Reaction with strong acids or bases may release toxic substances
Conditions to Avoid: Excess heat, open flames, sources of ignition, direct sunlight, moisture
Incompatible Materials: Strong oxidizing agents, strong acids, bases, metal salts
Hazardous Decomposition Products: Sulfur dioxide, nitrogen oxides, carbon monoxide, carbon dioxide, aniline

Toxicological Information

Acute Toxicity: Oral LD50 (rat): approximately 1200 mg/kg, may cause gastrointestinal disturbances and central nervous system effects
Skin Corrosion/Irritation: Causes moderate to severe irritation on contact
Serious Eye Damage/Irritation: Causes irritation, risk of serious eye injury
Respiratory Sensitization: Inhalation of dust may cause respiratory tract irritation, coughing, and breathing discomfort
Chronic Effects: Prolonged or repeated exposure may cause methemoglobinemia, affecting blood oxygen transport
Carcinogenicity: Not classified as a carcinogen by IARC/OSHA/NTP
Mutagenicity: No conclusive evidence of mutagenic effects
Reproductive Toxicity: Animal studies suggest possible risk to fertility with prolonged exposure, data for humans limited
Other Effects: May cause headache, dizziness, and blue coloration of skin (cyanosis) due to blood disorders

Ecological Information

Ecotoxicity: Harmful to aquatic organisms, risk of long-term adverse effects in the aquatic environment
Persistence and Degradability: Partially biodegradable, but may persist under some environmental conditions
Bioaccumulative Potential: Low to moderate potential, limited data available
Mobility in Soil: Water soluble, likely to migrate through soil and contaminate groundwater
Other Adverse Effects: Large releases may disrupt local ecosystems, especially if reaching water bodies; avoid uncontrolled discharge to environment

Disposal Considerations

Waste Disposal Methods: Dispose in accordance with local, regional, and national regulations for hazardous chemical waste
Contaminated Packaging: Triple rinse containers, dispose as hazardous waste
Sewage Disposal: Prohibited, do not discharge to municipal wastewater or storm drains
Recommended Treatment: Incineration in approved facility
Disposal Precautions: Do not mix with household waste, clearly label waste containers, document all waste handling for auditing

Transport Information

UN Number: 2585
Proper Shipping Name: Aniline derivatives, solid
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels: Toxic
Special Precautions for User: Avoid release during transportation, keep containers upright, document transfer chain
Environmental Hazards: Toxic to aquatic life, emergency procedure guides must be available during transport
Transport in Bulk: Follow appropriate regulations for land, air, or sea as applicable, confirm compatibility with container materials

Regulatory Information

Safety, Health, and Environmental Regulations: Listed in TSCA Inventory, subject to SARA Title III reporting, complies with REACH standards for chemical substances
Labeling Requirements: Comply with OSHA Hazard Communication Standard, all containers to display GHS pictograms and warnings
Restrictions: Use subject to workplace exposure controls and environmental release limits as set by local authorities
International Regulations: Controlled under international chemical transport conventions, EU CLP Regulation compliance required
Notification Obligations: Spills, releases, or accidental exposure must be reported as required under environmental protection laws
Workplace Classification: Designated as hazardous material for workplace inventory and safety planning
User Protection: Adherence to prescribed protocols ensures compliance with legal and ethical responsibilities for worker and environmental protection