Product Name: 4-Toluenesulfonic Acid
Synonyms: p-Toluenesulfonic acid, p-Toluene sulphonic acid, Tosylic acid
Chemical Formula: C7H8O3S
CAS Number: 104-15-4
Relevant Uses: Organic synthesis, acid catalyst in esterification, polymer industries
Manufacturer or Supplier: Chemical distributor contact details on label
Emergency Contact: Listed phone number for chemical emergencies
GHS Classification: Skin corrosion/irritation (Category 1B), Serious eye damage/eye irritation (Category 1), Acute toxicity-oral (Category 4)
Pictogram: Corrosive, exclamation mark
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage; Harmful if swallowed; Causes serious eye damage
Precautionary Statements: Avoid contact with eyes, skin, and clothing; Wear protective gear; Use ventilation; Do not breathe dust or mists
Potential Health Effects: Inhalation causes respiratory tract irritation; Oral contact leads to burns or gastrointestinal issues; Skin or eye exposure results in burns
Chemical Identity: 4-Toluenesulfonic Acid
Concentration: >98% by weight
Impurities: Water (<1%), trace organics from manufacture
Molecular Weight: 172.20 g/mol
TSCA Status: Listed
Inhalation: Move to fresh air; seek medical attention if irritated
Skin Contact: Remove contaminated clothes; rinse thoroughly with water for at least 15 minutes; medical attention recommended
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses; consult an ophthalmologist
Ingestion: Rinse mouth; do not induce vomiting; medical attention needed right away
Most Important Symptoms: Severe burns, irritation, redness, blistering, vision impairment
Notes for Physician: Treat symptomatically; monitor airway function due to risk of edema
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray for small fires
Unsuitable Media: No data against standard suppression methods
Hazardous Combustion Products: Sulfur oxides, carbon oxides, toxic fumes
Special Equipment: Wear self-contained breathing apparatus, chemical resistant suit
Advice for Firefighters: Fight fire from safe distance; prevent runoff from contaminating waterways
Personal Precautions: Evacuate area, wear chemical protective clothing, use respiratory protection
Environmental Precautions: Prevent runoff to drains, soil, or water sources; notify proper local authorities if contamination occurs
Cleanup Methods: Sweep up avoiding dust generation; neutralize with sodium bicarbonate; place waste in labeled containers for disposal
Decontamination: Wash spill site after material pickup; ventilate area
Safe Handling: Use local exhaust ventilation; avoid contact with acids, oxidizers, and bases; prevent inhalation of dust
Storage Conditions: Keep containers tightly closed; store in cool, dry, well-ventilated area; protect from moisture and direct sunlight
Incompatible Materials: Oxidizing agents, metals, bases
Packaging Material: Use corrosion-resistant containers; lined steel or polyethylene preferred
Occupational Exposure Limit: No ACGIH or OSHA limits established
Engineering Controls: Chemical fume hood or local exhaust ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), long-sleeve lab coat, splash goggles or face shield, NIOSH-approved respirator in case of dust
Hygiene Measures: Wash hands after handling; ensure facilities for eyewash and safety shower nearby
Appearance: White to pale crystalline solid
Odor: Slight aromatic odor
Melting Point: 103-106°C
Boiling Point: Decomposes at >140°C
Solubility: Readily soluble in water, alcohols, and ether
pH: 1 (10 g/L in water)
Vapor Pressure: Negligible at room temperature
Density: 1.34 g/cm³
Flash Point: Not flammable under typical conditions
Partition Coefficient (n-octanol/water): No data available
Chemical Stability: Stable under normal storage and handling
Conditions to Avoid: Moisture, excessive heat, dust formation
Incompatible Materials: Strong oxidizers, bases, metal powders
Hazardous Decomposition Products: Sulfur oxides, toluene, carbon oxides
Polymerization: No hazardous polymerization reported
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 oral (rat) 2,480 mg/kg
Skin Corrosion/Irritation: Causes burns; can be severe with prolonged contact
Serious Eye Damage/Irritation: Causes serious damage including risk of blindness
Respiratory Sensitization: Irritates the respiratory tract
Chronic Effects: No strong evidence of teratogenicity, carcinogenicity, or mutagenicity
Sensitization: Not known to cause allergic reactions
Ecotoxicity: Harmful to aquatic life with long lasting effects
Aquatic Toxicity: EC50 (Daphnia magna, 48h): 55 mg/L
Persistence and Degradability: Moderately biodegradable (under aerobic conditions)
Bioaccumulative Potential: Low expected bioaccumulation
Mobility in Soil: High mobility in aqueous systems
Other Comments: Avoid uncontrolled releases into environment
Waste Disposal: Dispose of in accordance with state, federal and local environmental control regulations
Recommended Disposal Method: Incineration in chemical waste facility if permitted; avoid landfill for corrosive substances
Container Disposal: Triple rinse containers; dispose as hazardous chemical waste
Precautions: Do not allow product or waste to enter water courses or drains
UN Number: 2585
UN Proper Shipping Name: p-Toluenesulfonic acid
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: III
Marine Pollutant: Not regulated as a marine pollutant
Special Precautions: Secure packaging, avoid physical damage and moisture contact
Transport Label: Corrosive
US TSCA: Listed
EU REACH Status: Registered
US SARA Title III: Not subject to reporting under Sections 302, 304, 311, or 312
California Proposition 65: Not listed
Canada DSL/NDSL: Listed on DSL
Other Regulations: Classified as hazardous according to OSHA Hazard Communication Standard 29 CFR 1910.1200
Labeling Requirements: GHS-compliant hazard and precautionary statements, pictograms, product identifier
