Product Name: 4-Morpholinopropanesulphonic Acid
Synonyms: MOPS, Morpholinepropane Sulfonic Acid
Chemical Formula: C7H15NO4S
CAS Number: 1132-61-2
Recommended Use: Laboratory chemical, buffer agent in biological research
Manufacturer/Supplier: Research chemical suppliers, university stores
Emergency Contact: Refer to local emergency procedures and relevant contacts assigned by the laboratory.
Classification: Not classified as a hazardous substance under GHS criteria
Label Elements: No required pictogram, signal word, or hazard statement
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Symptoms: May cause mild irritation to eyes, skin, and respiratory tract if large quantities are handled improperly
Long-term Effects: Data for chronic exposure is limited; prudent handling recommended
Target Organs: Eyes, skin, mucous membranes
Special Hazards: Not expected to pose a significant risk, but always avoid dust and direct contact.
Chemical Name: 4-Morpholinopropanesulphonic Acid
Purity: ≥99% (analytical grade)
Other Constituents: Trace water or impurities may be present at low percentages
Impurities: Not considered significant for laboratory-scale buffer use.
General Advice: Move affected person from exposure, assess breathing and circulation
Inhalation: Move to fresh air, seek medical attention if symptoms persist
Skin Contact: Rinse with water and soap, seek care if rash or irritation develops
Eye Contact: Flush eyes with water for at least 15 minutes, lift eyelids, contact physician if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, obtain medical advice
Note to Physicians: Symptomatic treatment only; no specific antidote.
Suitable Extinguishing Media: Use foam, dry chemical, carbon dioxide, or water spray
Special Fire Hazards: Decomposition may form hazardous fumes
Personal Protective Equipment: Wear self-contained breathing apparatus, chemical-resistant suit
Advice for Firefighters: Approach fire from upwind, avoid inhalation of combustion products, use water spray to cool containers
Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides possible.
Personal Precautions: Use protective gloves, goggles, avoid inhalation of dust
Environmental Precautions: Prevent entry into drains, sewers, soil, or waterways
Spill Cleanup Methods: Sweep up and collect into suitable containers for disposal
Decontamination: Wash spill area with soap and water to remove residue
Containment: Use inert absorbent material for liquid spills, minimize dust generation.
Handling: Keep containers tightly closed, avoid contact with skin and eyes, use local exhaust ventilation in enclosed spaces, wash hands after use, handle in a chemical fume hood for bulk quantities
Storage Requirements: Store in a cool, dry, well-ventilated area, away from incompatible substances like strong oxidants, acids, and bases, keep container tightly closed and labeled, avoid freezing
Storage Temperature: Room temperature recommended, typically 15-25°C
Other Precautions: Do not eat or drink during handling, store away from food and drink.
Exposure Limits: No occupational exposure limits assigned
Engineering Controls: Laboratory fume hood or adequate ventilation
Personal Protective Equipment: Chemical safety goggles, nitrile gloves, lab coat
Respiratory Protection: Respiratory protection not required under normal conditions, use NIOSH-approved mask if dust generated
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing, prohibit smoking, eating, or drinking in work areas.
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: Around 195–205°C
Boiling Point: Not applicable (decomposes)
Solubility: Highly soluble in water
Density: Approximately 1.2 g/cm³
pH: 2.5–4.5 in 0.1M solution
Vapor Pressure: Negligible
Flash Point: Not flammable under normal conditions
Partition Coefficient: Not determined.
Chemical Stability: Stable under normal laboratory conditions
Reactivity: Inert to most common substances
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, carbon oxides can develop under fire
Polymerization: Will not occur.
Acute Toxicity: Low expected toxicity, minimal symptoms reported at high concentrations
Routes of Exposure: Skin, eyes, inhalation, ingestion
Symptoms: May irritate skin, eyes, upper respiratory tract if mishandled
Sensitization: No evidence of skin or respiratory sensitization in animal studies
Carcinogenicity: No components listed as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Not considered mutagenic based on currently available information
Reproductive Toxicity: No evidence based on animal testing
Chronic Effects: No data available for prolonged exposure, prudent practice required.
Ecotoxicity: Not expected to be harmful at small quantities typically used in labs, large spills to aquatic environments may affect water quality
Persistence and Degradability: Biodegradable over time
Bioaccumulative Potential: Low, unlikely to bioaccumulate in natural systems
Mobility in Soil: High mobility in aqueous environments due to water solubility
Other Adverse Effects: Avoid excessive release to environment, ensure proper disposal and containment.
Waste Treatment Methods: Dispose of as laboratory chemical waste, do not discharge to drain
Disposal Containers: Use sealed chemical waste containers, label correctly
Incineration: Chemical incinerator preferred if facility permits
Regulatory Requirements: Follow local, state, and federal hazardous waste regulations
Contaminated Packaging: Rinse and dispose as chemical waste
Environmental Precautions: Keep out of water sources and soil, avoid landfill disposal if possible.
UN Number: Not regulated for transport
UN Proper Shipping Name: Not assigned
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not regulated
Environmental Hazards: None identified
Special Precautions: Avoid rough handling, keep packaging intact
Regulatory Agency Guidance: Consult latest local regulations for exceptions and special requirements.
Safety, Health, and Environmental Regulations: Product is not listed as hazardous under OSHA, REACH, or TSCA, but general chemical hygiene should prevail
SARA Section 313 (Title III): Not subject to reporting
California Prop 65: Not listed
TSCA Inventory Status: Listed
Other Regulations: For laboratory use only, follow institutional requirements and safety protocols, safety data sheet available upon request, updates reported to responsible parties in case of changes in classification or controls.
