Material Safety Data Sheet for 4-Methoxy-Aniline-2-Sulfonic Acid

Identification

Product Name: 4-Methoxy-Aniline-2-Sulfonic Acid
Synonyms: 2-Amino-5-Methoxybenzenesulfonic Acid
CAS Number: 98-44-2
Recommended Use: Dye intermediate, organic synthesis
Manufacturer: Chemical supplier information required
Contact Numbers: Emergency: Local Poison Control Center
Address: Refer to supplier's documentation

Hazard Identification

Classification: Harmful if swallowed, toxic in contact with skin, causes serious eye irritation
Signal Word: Warning
Hazard Statements: Harmful by inhalation, will cause irritation to skin and mucous membranes, poses risk of sensitization through repeated exposure
Pictogram: Exclamation mark, Health hazard
Precautionary Statements: Wear appropriate personal protective clothing, avoid breathing dust, prevent release into the environment, wash thoroughly after handling
Target Organs: Eyes, skin, respiratory system

Composition / Information on Ingredients

Chemical Identity: 4-Methoxy-Aniline-2-Sulfonic Acid
Molecular Formula: C7H9NO4S
Molecular Weight: 203.22 g/mol
Component: 4-Methoxy-Aniline-2-Sulfonic Acid (purity > 98%)
Impurities: Trace levels of related aromatic amines
Allergens: Not established

First Aid Measures

Inhalation: Move person to fresh air, keep at rest, support breathing with medical oxygen if needed, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash affected area with soap and water for at least 15 minutes, seek medical assistance if irritation or symptoms occur
Eye Contact: Rinse with plenty of water for at least 15 minutes, hold eyelids open, remove contact lenses if present, obtain medical attention immediately
Ingestion: Rinse mouth, do not induce vomiting, obtain medical care promptly
General Advice: Show MSDS and product label to physician

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: Avoid high-pressure water stream as powder may become airborne
Specific Hazards: Combustion produces toxic fumes including nitrogen oxides, sulfur oxides, and carbon monoxide
Protection: Firefighters wear self-contained breathing apparatus and full protective gear
Explosion Data: Material not known to be explosive
Firefighting Instructions: Evacuate area, cool containers exposed to fire with water, contain run-off to prevent environmental contamination

Accidental Release Measures

Personal Protection: Use face protection, gloves, chemical-resistant clothing
Environmental Precautions: Avoid release to soil, drains, surface water, contain spills with dikes or absorbents
Spill Response: Ventilate area, sweep up using non-sparking tools, place material in appropriate labeled waste containers, do not generate dusty conditions
Decontamination: Wash spill site with soap and water after material pickup is complete, prevent runoff into waterways
Disposal: Dispose of as chemical waste in accordance with local regulations

Handling and Storage

Handling: Use only in well-ventilated areas, minimize dust formation, avoid breathing vapors or particulates, wear protective equipment, avoid contact with skin and eyes
Hygiene: Wash hands thoroughly after handling, do not eat, drink, or smoke in work areas, launder contaminated clothing before reuse
Storage: Keep tightly closed in a cool, dry, well-ventilated area, store away from oxidizing agents and acids, protect from moisture
Incompatibilities: Strong oxidizers, strong acids
Storage Location: Dedicated chemical storage with secondary containment

Exposure Controls and Personal Protection

Occupational Limits: No specific OSHA, ACGIH, or NIOSH exposure limits set, minimize exposure as much as possible
Engineering Controls: Use local exhaust ventilation or fume hood, maintain eyewash stations and safety showers nearby
Respiratory Protection: Approved respirator with chemical filter for dusts and organic vapors
Skin Protection: Chemical-resistant gloves (nitrile or neoprene), long sleeves, laboratory coat
Eye Protection: Chemical splash goggles, face shield if handling large quantities
Environmental Controls: Prevent chemical runoff or uncontrolled release, treat contaminated air or water before discharge

Physical and Chemical Properties

Form: Crystalline powder
Color: White to pale yellow
Odor: None or faint aromatic
Melting Point: 225-230°C (decomposition may occur)
Boiling Point: Not applicable under ambient conditions
Solubility: Soluble in water, slightly soluble in ethanol
Density: 1.49 g/cm³
pH: Acidic (aqueous solution)
Vapor Pressure: Not measured for this compound, considered negligible
Partition Coefficient (log Kow): Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Instability: Material sensitive to high temperatures, decomposes on strong heating
Polymerization: No risk of hazardous polymerization
Incompatible Materials: Avoid mixing with oxidizers, acids, strong reducing agents
Decomposition Products: May emit oxides of nitrogen, sulfur, and carbon on burning
Reactivity: No known hazardous reactions under normal usage

Toxicological Information

Acute Toxicity: Harmful by ingestion (oral LD50 estimated 500–2000 mg/kg in rats), moderate irritation on skin contact
Chronic Effects: Prolonged exposure can cause dermatitis or respiratory sensitivity
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Mutagenicity: No reliable data available
Reproductive Toxicity: Not expected based on available information
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Rash, redness, coughing, eye discomfort, nausea with significant exposure

Ecological Information

Ecotoxicity: Harmful to aquatic life, avoid release into natural waterways
Persistence and Degradability: Moderately persistent, biodegradation data limited but aromatic sulfonic acids typically degrade slowly
Bioaccumulation: Expected to have low potential for bioaccumulation
Mobility in Soil: Compound expected to leach due to water solubility
Other Harmful Effects: Unchecked runoff contaminates surface water and may disrupt aquatic systems

Disposal Considerations

Waste Disposal: Dispose of in accordance with local, regional, national regulations as hazardous chemical waste
Method: Incineration in approved facility recommended, chemical must not be disposed in regular trash or pour down the drain
Contaminated Packaging: Rinse and dispose of container as hazardous waste
Special Precautions: Use PPE when disposing, label waste containers clearly

Transport Information

UN Number: Not assigned for most shipments, check national regulations
Transport Hazard Class: Not regulated under most transportation authorities when shipped as a solid, verify current status
Packing Group: Not classified
Labeling: Indicate as chemical substance, proper packaging to prevent leaks
Special Transport Precautions: Protect from moisture, avoid breaking containers, keep with compatible chemicals only

Regulatory Information

TSCA Status: Listed or exempted in the United States
EINECS/ELINCS: Listed in European inventories
Canada DSL/NDSL: Check specific component lists
SARA Title III: Not subject to Section 302 or 313 reporting
California Proposition 65: Does not appear on any state or federal carcinogen lists
Other: Always refer to local and regional chemical safety regulations