Product Name: 4-Anilinesulfonic Acid
Synonyms: p-Aminobenzenesulfonic acid, Sulfanilic acid
Chemical Formula: C6H7NO3S
CAS Number: 121-57-3
Manufacturer Information: Usually listed on container; emergency contact information is found on supplier’s website
Recommended Use: Dye and pigment intermediate, analytical reagent, research applications
Restrictions: Not intended for food, drug, or household use
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity – oral (Category 5)
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, potentially harmful by ingestion
Pictogram: Exclamation mark
Signal Word: Warning
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, wear protective gloves and eye protection
Chemical Name: 4-Anilinesulfonic Acid
Common Name: Sulfanilic acid
Concentration: ≥99% pure
Impurities: May include trace amounts of related sulfonic acids and anilines depending on manufacturing process
Inhalation: Remove person to fresh air, seek medical advice if cough or discomfort persists
Skin Contact: Remove contaminated clothing, rinse skin with water for several minutes
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present, seek medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, consult physician immediately
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: Direct jet of water can scatter the material
Specific Hazards: Burning may release toxic fumes including nitrogen oxides, sulfur oxides
Protective Equipment: Wear self-contained breathing apparatus and full protective clothing
Special Procedures: Move containers away from fire, use water spray to cool closed containers
Personal Precautions: Use personal protective equipment including gloves, goggles, dust mask
Environmental Precautions: Prevent entry into drains, waterways, or soil
Cleanup Methods: Sweep up and collect in suitable closed containers for disposal, wash spill area with plenty of water, ventilate area
Safe Handling: Use only in well-ventilated areas, avoid generating dust, handle with care
Storage Requirements: Store in a tightly closed container, keep in a cool, dry, ventilated place away from incompatible substances such as oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids, bases
Storage Class: Chemical storage area for inorganic acids and related compounds
Engineering Controls: Local exhaust ventilation, eyewash stations, safety showers
Exposure Limits: No specific occupational exposure limits set; treat as nuisance dust (10 mg/m3 TWA for inhalable, 3 mg/m3 TWA for respirable dust)
Personal Protective Equipment: Gloves (nitrile or neoprene), chemical splash goggles, dust mask or respirator (P2 or N95), laboratory coat
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing, eat and drink only in designated areas
Appearance: White to tan crystalline powder
Odor: Odorless or slightly aromatic
Melting Point: 288–300°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Soluble in water (8.5 g/L at 20°C), slightly soluble in ethanol
pH: 4.6 (1% solution in water)
Partition Coefficient: log Kow < 1 (low potential to bioaccumulate)
Vapor Pressure: Negligible
Flash Point: Not flammable under normal conditions
Autoignition Temperature: No data
Chemical Stability: Stable under standard storage and handling conditions
Conditions to Avoid: High humidity, excessive heat, open flames
Incompatible Substances: Strong acids, alkalis, oxidizing agents
Decomposition Products: Toxic gases such as sulfur oxides, nitrogen oxides, ammonia
Hazardous Polymerization: Does not occur
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: LD50 (oral, rat) >2000 mg/kg
Skin Irritation: Can cause redness and discomfort
Eye Irritation: Causes serious eye irritation, redness, watering
Inhalation: May cause respiratory tract irritation, coughing
Chronic Effects: No clear evidence of carcinogenicity or reproductive toxicity in available studies
Sensitization: Not reported to cause skin sensitization in standard tests
Ecotoxicity: Low to moderate toxicity to aquatic organisms (EC50 48h Daphnia magna >100 mg/L)
Persistence and Degradability: Biodegradable but may persist under some conditions
Bioaccumulative Potential: Low (log Kow < 1)
Mobility in Soil: Expected to be mobile due to water solubility
Other Adverse Effects: Avoid uncontrolled release to the environment
Waste Treatment Methods: Dispose of by landfill or incineration at an approved facility in compliance with local, state, national regulations
Handling of Containers: Rinse empty containers before disposal, puncture to prevent reuse
Precautions: Do not discharge into waterways or public sewers
Recycling: Not practical for this substance
UN Number: Not regulated for transport under UN/IMDG/IATA
Proper Shipping Name: Not classified as dangerous goods
Hazard Class: None
Packing Group: None
Environmental Hazards: Not considered marine pollutant
Special Precautions: Transport in tightly sealed, correctly labeled containers
Chemical Inventories: Listed on TSCA (US), EINECS/ELINCS (EU), DSL (Canada), IECSC (China), ENCS (Japan)
OSHA Status: Not listed as a hazardous substance
SARA Title III: Not classified under Section 302/304/313
California Proposition 65: Not listed
REACH Status: Registered or pre-registered in the EU according to local use
Other Regulations: Follow all applicable workplace safety acts and chemical storage guidelines
