Product Name: (2S)-2-(2-Amino-5-Chlorophenyl)-4-Cyclopropyl-1,1,1-Trifluorobut-3-Yn-2-Ol Methanesulfonate (1:1.5)
Chemical Family: Aromatic amines, trifluorobutyne derivatives, organochlorines
Synonyms: No common synonyms found in standard references
Recommended Use: Research, industrial chemical synthesis, pharmaceutical intermediate
Supplier: [Contact manufacturing facility for details]
Emergency Contact: [Local or national emergency numbers for hazardous materials]
CAS Number: [Not specified; to be updated from manufacturing records]
Physical Hazards: Dust formation expected if powder; risk of static charges, inhalation risk in poorly ventilated environments
Health Hazards: Toxic if swallowed, inhaled, or absorbed through skin; may cause gastrointestinal effects, respiratory tract irritation, skin sensitization, eye damage
Environmental Hazards: Harmful to aquatic life with prolonged effects; dispersal into soil and water bodies may pose risks to local ecosystems
Label Elements: Pictograms include skull and crossbones, exclamation mark for respiratory or skin irritation, aquatic toxicity symbol; signal word “Danger” required
Precautionary Statements: Avoid breathing dust or vapors, keep away from waterways, wash exposed skin thoroughly after handling, do not eat, drink, or smoke when using the product; wear eye and face protection
Chemical Name: (2S)-2-(2-Amino-5-Chlorophenyl)-4-Cyclopropyl-1,1,1-Trifluorobut-3-Yn-2-Ol Methanesulfonate (1:1.5)
Purity: >95% (typical for laboratory-grade sample)
Impurities: May contain unreacted starting materials, trace solvents <0.5%, non-volatile residues <1%
Hazardous Ingredients: No additional hazardous components above 1% threshold except proprietary process-related traces
Inhalation: Move affected person to fresh air, monitor for signs of respiratory distress, seek medical attention if symptoms persist or develop
Skin Contact: Remove contaminated clothing and shoes, wash skin thoroughly with soap and water, do not use solvents or thinners, medical attention required if irritation continues
Eye Contact: Rinse immediately under running water for at least 15 minutes, lift upper and lower eyelids, seek prompt ophthalmologic evaluation
Ingestion: Rinse mouth with water, do not induce vomiting, give small quantities of water if victim is conscious, obtain medical care, provide details on chemical for treatment guidance
Most Important Symptoms: Irritation, localized burns, airway difficulty, allergic reactions, possible delayed effects on liver and kidneys
Suitable Extinguishing Media: Use dry chemical powder, foam, or carbon dioxide; water spray recommended for larger fires/oil containment
Unsuitable Media: Avoid direct water jet which could spread solid or dust clouds containing chemical
Fire Hazards: Toxic, corrosive, and irritating gases (such as hydrogen chloride, nitrogen oxides, sulfur oxides, and hydrogen fluoride) may form during combustion
Protective Equipment: Full protective suit, self-contained breathing apparatus; keep containers cool by spraying with water if exposed to fire
Other Advice: Move unaffected materials from fire zone, avoid exposure to vapors, dike fire control water for later disposal if possible
Personal Precautions: Stop release at source, evacuate unnecessary personnel from affected area, ventilate, avoid creating dust or aerosol
Protective Equipment: Nitrile gloves, chemical splash goggles, lab coat, suitable vapor/powder respirator (P3/organic vapor/acid gas cartridge)
Environmental Precautions: Prevent from entering drains, watercourses, and soil, report significant spills to environmental authorities
Clean-Up Methods: Sweep or vacuum solid/spilled powder using tools resistant to corrosion, collect in suitably labeled containers, wipe area with damp cloth using appropriate solvent if safe
Disposal: Follow local regulations regarding hazardous chemical disposal; decontaminate spill area after removal
Handling: Use in fume hood or well-ventilated area, minimize dust generation, handle with nitrile or butyl gloves, do not mix with strong acids or bases; avoid contact with eyes, skin, or clothing
Storage: Keep tightly sealed in original labeled packaging, store away from incompatible materials such as strong oxidizers or reducing agents or extremes of temperature; maintain in cool, dry place out of direct sunlight. Store below 25°C
Other Guidance: Keep away from food and beverages; follow defined housekeeping procedures to avoid contamination; use only with chemical safety training
Exposure Limits: No established ACGIH/TLV or OSHA PEL; minimize to lowest practical levels
Engineering Controls: Chemical fume hood or local exhaust ventilation required; eyewash and safety showers accessible in work area
Personal Protective Equipment: Splash proof chemical goggles, nitrile gloves, laboratory coat/gown, closed footwear, if risk of exposure high, certified respirator (APF ≥ 10 recommended)
Other Protection: Wash hands and exposed skin before breaks and after work, remove contaminated clothing and launder before reuse
Form: Pale yellow to yellow-brown crystalline solid or fine powder
Odor: Slight chemical odor, non-distinct
Melting Point: 155–165°C (specimen dependent)
Boiling Point: Data not available (may decompose before boiling)
Solubility: Soluble in DMSO, methanol, and acetonitrile; sparingly soluble in water
Density: Approx. 1.5 g/cm3 (estimated)
pH (aqueous suspension): Not determined, likely acidic
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): No reliable data; expect moderate logP due to aromatic and cyclopropyl content
Stability Under Ordinary Conditions: Stable at room temperature, out of direct sunlight, in airtight container
Chemical Stability: Stable if stored out of light and moisture at recommended temperature
Reactivity: May react with strong bases, oxidizing or reducing agents, or under elevated temperature
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, sulfur oxides, fluorinated degradation products as toxic gases/fumes
Conditions to Avoid: Contact with incompatible materials, excessive heat, sparks, static discharge
Polymerization: No hazardous polymerization expected under normal handling
Acute Toxicity: Experimental data limited; anticipated oral LD50 in rats under 200 mg/kg (based on related structures); inhalation exposure data not established
Chronic Effects: Possible organ toxicity with repeated exposure; animal studies indicate possible liver and kidney changes at high doses
Irritation: Eye, skin, and respiratory tract irritant; possible allergic response on repeat contact
Carcinogenicity: No data available; related compounds not classified as carcinogens by IARC, NTP, or OSHA
Mutagenicity: No mutagenicity data reported; treat as mutagenic unless proven otherwise
Other Effects: May cause headache, dizziness, nausea, or confusion at high doses or in poorly ventilated areas
Ecotoxicity: Harmful to fish, aquatic invertebrates, and algae at concentrations below 1 mg/L; risk of bioaccumulation in some organisms
Persistence and Degradability: Poorly biodegradable; main component resists hydrolysis, some environmental breakdown under sunlight likely produces toxic fragments
Mobility in Soil: Likely to bind to soil particles, but some components may leach to groundwater due to partial water solubility
Other Adverse Effects: Long-term release can cause toxic build-up in aquatic environments; avoid uncontrolled disposal
Waste Disposal Methods: Treat as hazardous waste; incinerate in approved chemical incinerator with afterburner and scrubber
Container Disposal: Rinse empty containers with suitable solvent and water, dispose of residues and containers as hazardous chemical waste per local guidelines
Other Instructions: Do not discharge to public wastewater or natural environment; consult local/regional regulatory authorities for authorized chemical treatment or disposal contractors
UN Number: To be assigned based on specific composition and hazard class verification
Shipping Name: Toxic solid, organic, n.o.s. (contains aromatic amine, trifluorobutyne derivative)
Hazard Class: 6.1 (Toxic substances)
Packing Group: II (moderate hazard)
Environmental Hazards: Product packed to prevent leaks during transport, strong labeling and documentation required for international shipping (IMDG, IATA, ADR compliance)
Special Precautions: Transport only in containers tightly sealed and clearly labeled, avoid contact with incompatible materials, check carrier acceptance and emergency protocols
OSHA Status: Not specifically listed; general duty to protect workers from chemical hazards applies
TSCA/REACH: May require notification or approval before import, use, or disposal depending on jurisdiction; not listed on US TSCA Inventory
SARA Title III: Not classified as extremely hazardous, but toxic chemical reporting may be required under Section 313 depending on use quantities
California Proposition 65: Not listed; verify updates regarding related aromatic amines
Other National/International Regulations: May fall under controlled substance rules and require record keeping/logs due to research or pharmaceutical relevance; safety training and risk minimization measures required
