Product Name: 2 N Carbamoymethylamino Ethanesulfonic Acid
Synonyms: CAPS Buffer, N-cyclohexyl-3-aminopropanesulfonic acid
CAS Number: 1135-40-6
Molecular Formula: C9H19NO3S
Intended Use: Laboratory chemical, buffer in biochemical and molecular biology research
Manufacturer Contact: Safety office, chemical supplier, or laboratory supervisor
Emergency Phone Number: Refer to institutional protocol or regional Poison Control Center
Supplier Identification: Academic or industrial chemical distributor details required upon purchase
Classification: Not classified as hazardous according to Global Harmonized System (GHS)
Label Elements: Product does not fall under known hazard class labels
Signal Word: No signal word required
Hazard Statements: May generate irritation to eyes, skin, and respiratory system upon exposure
Precautionary Statements: Use personal protective equipment; avoid contact with skin and eyes; do not breathe dust; wash hands thoroughly after handling
Physical Hazards: Dust may cause mechanical irritation
Health Hazards: Short-lived skin or eye irritation may arise after contact; prolonged exposure could cause mild respiratory effects for sensitive individuals
Environmental Hazards: Not expected to be environmentally hazardous in small laboratory quantities
Chemical Identity: 2-(N-carbamoylmethylamino)ethanesulfonic acid
Chemical Formula: C9H19NO3S
Component: 2 N Carbamoymethylamino Ethanesulfonic Acid, Purity >99%
CAS Number: 1135-40-6
Impurities/Additives: Trace moisture, inorganic salts may be present (<0.1%)
Mixture or Substance: Single component substance
Hazardous Components: No known hazardous ingredients under GHS guidelines
Inhalation: Move person to fresh air and keep at rest, seek medical attention if symptoms persist, breathe comfortably
Skin Contact: Remove contaminated clothing, rinse skin with water, use mild soap and water as needed, seek medical attention if irritation develops
Eye Contact: Rinse with running water for minimum 15 minutes, remove contact lenses if present, continue flushing, obtain medical help if irritation continues
Ingestion: Rinse mouth thoroughly with water, never induce vomiting without professional advice, call medical professional or Poison Control
Note to Physicians: Provide symptomatic and supportive care, no known specific antidote
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry powder, or appropriate foam
Special Hazards: No unusual fire or explosion hazard, upon thermal decomposition may release sulfur oxides, nitrogen oxides, carbon monoxide, and carbon dioxide
Firefighter Precautions: Wear self-contained breathing apparatus, full protective clothing
Firefighting Strategy: Move containers from fire area if possible; cool adjacent containers with water spray
Combustion Products: Sulfur oxides, nitrogen oxides, carbon oxides, unidentified toxic fumes possible
Personal Precautions: Avoid dust formation, ventilate area, use personal protective equipment including gloves and goggles
Environmental Precautions: Prevent entry of bulk product into drains, waterways, soil
Method for Containment: Sweep or shovel spilled product, avoid creating dust, place in appropriate waste container
Clean-Up Procedures: Wash spill site with plenty of water after material removal, dispose all cleaning materials per local regulation
Emergency Procedures: Contact emergency services for large or uncontrolled spills, evacuate area if needed
Handling: Keep away from incompatible substances such as strong acids, bases, oxidizers; avoid inhaling powder; handle with dry, clean hands using proper PPE
Storage Conditions: Store in a tightly closed container in a cool, dry, well-ventilated location; avoid exposure to moisture and direct sunlight
Storage Compatibility: Separate from food, oxidizing agents, strong acids and bases
Recommended Storage Temperature: 15 – 25°C, desiccated environment
Other Precautions: Clearly label all storage containers, limit access to trained personnel
Engineering Controls: Use laboratory fume hood, local exhaust ventilation as necessary for dust control
Eye Protection: Chemical safety goggles
Skin Protection: Lab coat, impervious gloves recommended
Respiratory Protection: Dust mask or respirator (NIOSH approved) if handling solid or generating dust
Other Protective Equipment: Emergency eyewash, safety shower nearby
Exposure Limits: No occupational exposure limits established by OSHA, NIOSH, ACGIH; maintain good laboratory hygiene
Appearance: White crystalline solid or powder
Odor: Odorless
Melting Point: Approx. 200°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water, slightly soluble in alcohol
pH (1% solution): Approximately 10.4
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.3 g/cm³
Partition Coefficient (log Kow): No data
Other Data: Non-volatile, hygroscopic
Chemical Stability: Stable under standard laboratory and storage conditions
Possibility of Hazardous Reactions: No hazardous polymerization expected
Conditions to Avoid: Moisture, excessive heat, exposure to strong acids and oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids, reducing agents
Hazardous Decomposition Products: Oxides of carbon, nitrogen, sulfur on burning
Reactivity: No dangerous reactions known under recommended handling
Acute Toxicity: Low acute oral and dermal toxicity based on available animal data
Skin Corrosion/Irritation: May cause irritation after prolonged exposure
Eye Damage/Irritation: Dust or solution may irritate the eyes
Respiratory Sensitization: Inhalation of dust may cause temporary cough or sneezing
Chronic Effects: No known long-term effects or sensitization risk in typical lab use
Carcinogenicity/Mutagenicity: No evidence from animal or in vitro studies
Additional Data: Handle substances with care regardless of low toxicity assessment
Aquatic Toxicity: Not expected to cause significant harm in aquatic environments in standard laboratory quantities
Persistence and Degradability: Biodegradability not well characterized; likely to degrade over time in environment
Bioaccumulative Potential: Expected low potential for bioaccumulation
Mobility in Soil/Water: Soluble, possible mobility in water
Other Adverse Effects: Dispose according to applicable regulations, do not allow into large bodies of water, avoid unnecessary release
Waste Disposal: Collect solid or liquid waste in clearly labeled chemical waste containers
Method of Disposal: Incinerate or landfill in compliance with local, regional, national, and international regulations
Contaminated Packaging: Triple rinse containers, deface label, dispose as lab chemical waste
Other Recommendations: Avoid sewer disposal, consult institutional hazardous waste services before disposal
UN Number: Not regulated for transport
Proper Shipping Name: Not dangerous goods
Transport Hazard Class: Non-hazardous
Packing Group: None
Marine Pollutant: No
Special Transport Precautions: Protect from moisture, use secure, sealed containers
International Inventories: Listed on TSCA (USA), DSL (Canada), REACH (EU), and other key national inventories
SARA Title III (Sections 302, 311/312, 313): Not listed
California Proposition 65: Not subject to warning or restrictions
Other Regulation: Not classified as hazardous under OSHA Hazard Communication Standard
Workplace Classification: General laboratory chemical; restrict access to trained personnel
Labeling: Follow chemical hygiene plan; standard workplace safety labeling recommended
