Material Safety Data Sheet for 2-Morpholinoethanesulphonic Acid

Identification

Chemical Name: 2-Morpholinoethanesulphonic acid
Common Names: MES Buffer, MES
CAS Number: 4432-31-9
EINECS Number: 224-618-7
Recommended Use: Laboratory reagents, chemical research, biological and biochemical buffer
Manufacturer Information: Supplier contact details, address, phone number, emergency contact

Hazard Identification

Classification: Not classified as hazardous according to GHS
Potential Health Effects: May irritate eyes, skin, and respiratory tract on contact
Hazard Statements: Causes mild irritation to skin or eyes
Precautionary Statements: Avoid breathing dust, avoid contact with skin and eyes, wash thoroughly after handling
Label Elements: Pictograms none required, Signal Word none, no specific hazard symbol

Composition / Information on Ingredients

Chemical Identity: 2-Morpholinoethanesulphonic acid
Chemical Formula: C6H13NO4S
Molecular Weight: 195.24 g/mol
Concentration: ≥ 99% pure
Impurities: Possible trace solvents, no major hazardous impurities

First Aid Measures

Inhalation: Move affected person to fresh air, keep comfortable. Get medical attention if symptoms appear.
Skin Contact: Wash skin with soap and water, remove contaminated clothing.
Eye Contact: Rinse cautiously under running water for several minutes, lift eyelids to ensure complete removal. Seek medical attention if irritation persists.
Ingestion: Rinse mouth, do not induce vomiting. Give water to drink if conscious, seek medical advice immediately.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: None known
Special Hazards from Combustion: Forms hazardous gases such as nitrogen oxides, sulfur oxides under fire conditions
Protective Equipment for Firefighters: Use self-contained breathing apparatus, chemical-protective clothing, avoid exposure to decomposition products
Firefighting Instructions: Cool containers with water from a safe distance. Use only non-sparking tools in response areas.

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, protective clothing. Avoid inhalation of dust.
Environmental Precautions: Prevent entry into drains, waterways or soil.
Spill Cleanup Methods: Sweep up and collect in appropriate containers for disposal. Use damp cloth to reduce dust generation. Dispose of material according to local regulations.
Emergency Procedures: Evacuate area if necessary, follow all company safety procedures.

Handling and Storage

Safe Handling: Always use with proper ventilation. Handle with care to avoid spillage or dust formation. Do not eat, drink, or smoke during handling.
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated place, away from incompatible materials such as strong oxidizers or acids.
Incompatible Substances: Strong oxidizing agents
Storage Precautions: Keep container labeled and sealed when not in use.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No official exposure limits established
Engineering Controls: Work in fume hood or well-ventilated area. Use local exhaust or mechanical ventilation to minimize dust exposure.
Eye Protection: Safety goggles or face shield
Skin Protection: Lab coat, gloves made from nitrile or neoprene
Respiratory Protection: Dust mask or respirator if dust levels are high
Hygiene Measures: Wash hands thoroughly after use, remove contaminated clothing before entering eating areas.

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless
Melting Point: 300°C (decomposition)
Solubility: Highly soluble in water
pH (1% solution): Approximately 5.5–6.7
Boiling Point: Not determined
Vapor Pressure: Not applicable
Flash Point: Not applicable
Explosive Properties: No evidence of explosive hazard under normal handling

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions.
Reactivity: Not known to undergo hazardous reactions under normal use.
Conditions to Avoid: High heat, open flames, sources of ignition, incompatible materials.
Incompatible Materials: Strong oxidizers.
Hazardous Decomposition Products: May release toxic gases such as nitrogen oxides, sulfur oxides during decomposition.

Toxicological Information

Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Low oral and dermal toxicity expected based on available data
Skin/Eye Irritation: May cause mild irritation
Chronic Effects: No evidence of chronic toxicity in laboratory animals
Carcinogenicity: Not listed by IARC, NTP, OSHA
Other Effects: No data available regarding mutagenicity or reproductive toxicity

Ecological Information

Ecotoxicity: Expected to have low toxicity to aquatic life based on data for similar substances
Persistence and Degradability: Not expected to persist in the environment; readily biodegradable
Bioaccumulation: Low potential for bioaccumulation
Mobility in Soil: Highly soluble, may migrate in water systems
Other Adverse Effects: None known based on available research

Disposal Considerations

Waste Disposal Methods: Collect and contain material for disposal in accordance with local, regional, and national regulations.
Disposal of Contaminated Packaging: Triple-rinse containers before disposal or recycling, follow regulations for hazardous waste disposal.
Additional Considerations: Do not discharge untreated material into the environment or drains.

Transport Information

UN Number: Not regulated
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: None assigned
Label Required: None required
Special Transport Notes: Protect packaging from physical damage, store upright during transit, transport according to company procedures.
Environmental Hazards: Not classified as marine pollutant or environmentally hazardous

Regulatory Information

US TSCA: Listed
EINECS/ELINCS: Listed
REACH Status: Exempted for research purposes, not considered a substance of very high concern
OSHA Hazard Communication: Not classified as hazardous under OSHA criteria
SARA Title III: Not subject to reporting
Other Regulations: Observe all applicable local, regional, national, and international regulations regarding chemical handling