Material Safety Data Sheet for [(2-Methoxyphenyl)Amino]Methanesulphonic Acid

Identification

Chemical Name: [(2-Methoxyphenyl)Amino]Methanesulphonic Acid
Synonyms: 2-Methoxyaniline Methanesulfonic Acid, o-AnisidineMethanesulphonic Acid
CAS Number: Available upon request from suppliers
Manufacturer Information: Always confirm with your supply chain or in-house safety officers
Emergency Contact: Consult emergency response sheets available at storage site or local chemical supplier
Recommended Use: Restricted to research, laboratory analysis, or specific industrial applications authorized by regulatory frameworks

Hazard Identification

Classification: Acute toxicity (oral, inhalation, dermal), Skin Irritation, Eye Damage, Specific Target Organ Toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed, toxic in contact with skin or if inhaled, can cause severe skin burns and eye damage, suspected of causing cancer based on available chemical analogues
Pictograms: Skull and crossbones, corrosion, health hazard
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, use only in well-ventilated areas, keep away from food and drink

Composition / Information on Ingredients

Component: [(2-Methoxyphenyl)Amino]Methanesulphonic Acid
Purity: Typically greater than 98% based on supplier specifications
Impurities: Trace anilines, methoxy byproducts under 2%
Solvent: None or specified by batch documentation

First Aid Measures

Inhalation: Move person to fresh air, keep victim under observation for respiratory symptoms, seek immediate medical attention for difficulty breathing
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for 20 minutes, do not use neutralizing agents without medical direction
Eye Contact: Rinse cautiously with water for at least 15 minutes, lift upper and lower eyelids occasionally, call poison control or emergency medical team
Ingestion: Rinse mouth, drink small amounts of water if conscious, never induce vomiting except under medical direction, immediate professional evaluation recommended
Notes for Physicians: Treat symptomatically, monitor for delayed reactions especially those involving the liver or blood

Fire-Fighting Measures

Suitable Extinguishing Agents: Carbon dioxide, dry chemical powder, or foam suitable for chemical fires, do not use water jets
Specific Hazards: May release irritating or toxic fumes of sulfur oxides, nitrogen oxides, carbon monoxide when combusted
Protective Equipment: Firefighters require self-contained breathing apparatus, full protective gear including chemical-resistant coat and gloves
Special Procedures: Keep upwind, prevent runoff from reaching drains or surface waters, isolate immediate hazard area

Accidental Release Measures

Personal Precautions: Use appropriate personal protection including gloves, goggles, and an approved respirator, restrict access to affected area
Environmental Precautions: Prevent further leakage or spillage, contain chemical with non-reactive absorbent, avoid entry into groundwater or surface water
Cleanup Methods: Pick up using scoops or specialized vacuums, place in labeled chemical-waste containers, clean surface thoroughly with water and detergent, ventilate area

Handling and Storage

Handling: Use chemical fume hood or controlled ventilation, avoid generating dust or aerosols, follow established chemical hygiene plans, never eat or drink near working area
Storage: Store in tightly closed containers, keep in cool, dry, well-ventilated zone away from oxidants and incompatible materials, use secondary containment to reduce risks of spillage

Exposure Controls and Personal Protection

Engineering Controls: Ensure lab has eyewash stations and safety showers, use chemical fume hoods, avoid recirculation of air containing contaminants
Personal Protection Equipment: Chemical-resistant gloves (such as nitrile), safety goggles or full-face shield, long-sleeve lab coat, certified respirator if risk of inhalation
Exposure Limits: Refer to local occupational exposure standards, direct measurement of airborne concentrations strongly encouraged
Hygiene Practices: Wash hands before breaks and after work, remove contaminated clothing before leaving work area

Physical and Chemical Properties

Appearance: Off-white to light tan crystalline solid
Odor: Slight characteristic aromatic odor
Odor Threshold: Not readily available, unlikely to serve as a reliable warning
pH (1% solution): Typically acidic in water
Melting Point: Decomposes before reliable measurement possible, reference batch analytics
Solubility: Good in water, partial in polar organic solvents
Boiling Point: Not applicable under normal laboratory conditions due to decomposition
Vapor Pressure: Negligible at ambient temperature
Partition Coefficient (n-octanol/water): Information limited; expected moderate due to aromatic and sulphonic moieties
Flash Point: Not established

Stability and Reactivity

Chemical Stability: Stable under recommended storage, degrades with heat or strong acids/bases
Hazardous Reactions: Avoid strong oxidizing agents, strong acids or bases can lead to decomposition
Decomposition Products: Sulfur oxides, nitrogen oxides, carbon monoxide, possibly phenolic residues
Polymerization: Not known to occur under normal use

Toxicological Information

Acute Toxicity: Harmful by oral, dermal or inhalation exposure, symptoms may include headache, dizziness, nausea, cyanosis in high doses
Chronic Exposure: Prolonged or repeated exposure could potentially damage liver, kidneys, or blood based on chemical structural similarities
Skin/Eye Irritation: Causes severe irritation; prolonged contact may result in burns or permanent eye injury
Carcinogenicity: No direct human studies available; aromatic amine derivatives are generally considered possible or probable human carcinogens
Sensitization: May cause allergic reactions in sensitized persons
Mutagenicity: Limited information, handle as a potential mutagen for safety

Ecological Information

Aquatic Toxicity: Expected to be toxic to aquatic organisms, avoid direct release to the environment
Persistence and Degradability: Low degradation rate in natural settings, persists in aquatic habitats
Bioaccumulation Potential: Limited data; some risk due to aromatic content
Mobility in Soil: Moderately mobile; risk of groundwater contamination if spilled
Other Adverse Effects: Use best practices to minimize ecological harm, consult local environmental agencies for disposal and spill protection

Disposal Considerations

Waste Disposal: Treat as hazardous special waste, incinerate under controlled conditions, follow all local, regional, national, and international regulations
Container Handling: Triple rinse and render packaging unusable before disposal, do not reuse empty containers
Secondary Containment: Necessary when handling bulk quantities, collect and neutralize spills immediately

Transport Information

UN Number: Seek up-to-date regulatory listings from transportation authorities
UN Proper Shipping Name: Consult shipping documentation and supplier
Transport Hazard Class: Refer to chemical hazard classification, consult shipping company
Packing Group: Listed by shipment classification, usually group II or III for similar acids
Environmental Hazards: Mark as marine pollutant if shipped by sea, record special handling instructions

Regulatory Information

Labeling: Follow national/international chemical labeling rules, include hazard pictograms and statements
Inventory Listing: Check if substance is listed under TSCA, EINECS, DSL, or other government chemical inventories
Regulation Status: May require pre-market notification or restrictions due to toxicological profile
Worker Protection: Adhere to national occupational safety rules, provide training for all users
Other: Regularly review safety policies to reflect updates, maintain up-to-date MSDS access onsite