Material Safety Data Sheet for 2-Cyclohexylamino Ethanesulfonic Acid

Identification

Product Name: 2-Cyclohexylamino Ethanesulfonic Acid
Synonyms: CHES, N-Cyclohexyl-2-aminoethanesulfonic acid
CAS Number: 103-47-9
Formula: C8H17NO3S
Recommended Use: Laboratory reagent, buffer agent for biological and biochemical research
Supplier Name: Laboratory chemical supplier
Emergency Contact: Local poison control center or chemical safety officer

Hazard Identification

Classification: Not classified as hazardous under current GHS criteria, though may cause mild irritation
Label Elements: No pictogram expected, though standard precaution phrases apply
Hazard Statements: May irritate eyes, skin, and respiratory tract on exposure
Precautionary Statements: Use personal protective equipment, wash after handling, avoid dust generation, use adequate ventilation
Other Hazards: Prolonged or high exposure could lead to respiratory discomfort

Composition / Information on Ingredients

Chemical Name: 2-Cyclohexylamino Ethanesulfonic Acid
Concentration: 98-100% (typically provided as pure solid)
Other Components: No major impurities present in standard laboratory-grade product
Molecular Weight: 207.29 g/mol

First Aid Measures

Eye Contact: Rinse cautiously with water, remove contact lenses if possible, seek medical advice for persistent irritation
Skin Contact: Wash area thoroughly with plenty of water, remove contaminated clothing, seek attention if symptoms develop
Inhalation: Move person to fresh air, provide artificial respiration if needed, get medical help if symptoms persist
Ingestion: Rinse mouth with water, do not induce vomiting, seek prompt medical attention in case of discomfort or large amount swallowed
Special Notes for Medical Providers: Symptoms mostly mild and supportive care is sufficient; follow general practice for chemical exposures

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, or CO₂
Hazardous Combustion Products: Sulfur oxides, nitrogen oxides, possible toxic fumes
Personal Protective Equipment: Self-contained breathing apparatus, chemical-resistant clothing
Special Firefighting Procedures: Avoid inhalation of smoke, approach from upwind to avoid exposure

Accidental Release Measures

Personal Precautions: Minimize dust formation, wear gloves, safety goggles, and protective clothing
Environmental Precautions: Avoid release to sewers, surface water, or groundwater
Methods for Cleanup: Sweep up solid material, collect in appropriate waste containers for disposal, ventilate affected area, clean residue with water
Notification: Report significant spills to facility safety office or environmental authorities

Handling and Storage

Handling: Use in well-ventilated areas, minimize contact with skin and eyes, avoid dust generation, keep containers tightly closed
Storage: Store in cool, dry location away from incompatible chemicals, keep container sealed when not in use, protect from excessive heat and sunlight
Incompatibilities: Strong oxidizers, reactive acids

Exposure Controls and Personal Protection

Occupational Exposure Limits: No exposure limits established by OSHA, ACGIH, NIOSH
Engineering Controls: Use local exhaust ventilation or general room ventilation to keep airborne concentrations low
Personal Protective Equipment: Lab coat, gloves (nitrile, PVC), eye protection (goggles or face shield), dust mask or P2 respirator if airborne concentrations increase
Hygiene Measures: Wash hands after handling, avoid eating or drinking in work area

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or slight odor
Odor Threshold: Not established
pH (1% Solution): 9.0–10.0
Melting Point: Approximately 218–222 °C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility: Easily soluble in water
Specific Gravity: ~1.28
Vapor Pressure: Not significant at room temperature
Flash Point: Not flammable
Partition Coefficient (Log Kow): Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage and use conditions
Reactivity: No hazardous reactivity with normal laboratory chemicals
Hazardous Reactions: Strong oxidizers may cause rapid reaction
Decomposition Products: Sulfur oxides, nitrogen oxides when heated to decomposition
Conditions to Avoid: High temperatures, contact with strong oxidizing agents

Toxicological Information

Acute Toxicity: Low oral toxicity expected due to high molecular weight and water solubility; specific LD₅₀ data not available
Potential Health Effects: Exposure may cause mild eye, skin, or respiratory tract irritation
Sensitization: No evidence of sensitization or allergic reaction identified
Chronic Toxicity: No chronic effects reported in published literature
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Other Information: Handle according to general chemical safety protocols

Ecological Information

Aquatic Toxicity: Data unavailable, though buffer compounds like this may cause minor alteration to aquatic pH if released in large quantity
Persistence and Degradability: Not expected to be readily biodegradable, but significant accumulation unlikely
Bioaccumulation Potential: No evidence of bioaccumulation due to water solubility
Mobility in Soil: Moderate to high mobility in aqueous solutions
Other Adverse Effects: Minimize environmental release, do not dump into drains

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations via chemical waste facility
Product: Incineration or landfill approved for chemical waste; avoid entry into surface or groundwater
Contaminated Packaging: Triple rinse containers before disposal or reconditioning; follow lab safety protocols

Transport Information

UN Number: Not classified as hazardous for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not listed as marine pollutant
Special Precautions: Keep container protected against physical damage and moisture during shipment

Regulatory Information

OSHA: No specific standards
TSCA: Listed
EINECS/ELINCS: Listed
REACH Status: Exempt or registration not required for laboratory use
Hazard Symbols: None mandated
Other Regulations: Compliance with workplace safety and environmental guidelines advised for storage, use, and disposal