(1R)-(-)-10-Camphorsulfonic Acid Material Safety Data Sheet (MSDS)

Identification

Product Name: (1R)-(-)-10-Camphorsulfonic Acid
Synonyms: (1R)-(-)-10-Camphorsulphonic acid, CSA, 10-Camphorsulfonic acid
Chemical Formula: C10H16O4S
Molecular Weight: 232.30 g/mol
CAS Number: 5872-08-2
Recommended Use: Chiral resolving agent, organic synthesis
Supplier: Laboratory chemical supply companies
Contact Information: Refer to local supplier or manufacturer for emergency numbers, address, email, and phone support

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin corrosion/irritation, Eye damage/irritation
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, may be harmful if swallowed, causes respiratory irritation
Pictograms: Corrosive symbol, exclamation mark
Precautionary Statements: Avoid breathing dust or vapors, use only outdoors or in well-ventilated space, wear protective gloves and goggles, wash hands thoroughly after handling, store locked up
Routes of Exposure: Skin, eyes, inhalation, ingestion
Target Organs: Eyes, skin, respiratory system

Composition / Information on Ingredients

Chemical Name: (1R)-(-)-10-Camphorsulfonic Acid
Common Name: Camphorsulfonic acid
Purity: Typically >99%
Impurities: Minor impurities from manufacturing; specification sheets from supplier outline trace contaminants
CAS Number: 5872-08-2
Other Ingredients: No other components or hazardous impurities present above regulatory disclosure limits

First Aid Measures

Inhalation: Move exposed person to fresh air immediately, seek medical attention for breathing difficulty, loosen tight clothing
Skin Contact: Remove contaminated clothing and shoes, rinse skin with plenty of water for at least 15 minutes, contact healthcare provider for burns or persistent irritation
Eye Contact: Rinse with water for 15 minutes keeping eyelids open, remove contact lenses if easily possible, seek urgent medical attention
Ingestion: Rinse mouth with water, avoid inducing vomiting, never administer anything by mouth to an unconscious person, seek medical advice immediately
Most Important Symptoms: Burning sensation, redness, pain, blistering, respiratory irritation, possible gastrointestinal upset
Immediate Medical Care: Needed for exposure involving serious symptoms, especially with eyes, mucous membranes, significant inhalation or ingestion

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide; avoid high-pressure water jets
Special Hazards: Emits toxic fumes, including sulfur oxides and carbon oxides, under fire conditions
Protective Equipment for Firefighters: Full protective gear with self-contained breathing apparatus
Firefighting Procedures: Approach from upwind, remove containers from danger zone if safe
Flash Point: Not readily flammable in solid form
Unusual Fire/Explosion Hazards: Contact with strong oxidizers or bases may cause rapid reactions or decomposition

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, safety goggles, and suitable protective clothing to prevent skin and eye contact; avoid raising dust
Emergency Procedures: Evacuate unnecessary personnel, ventilate area, prevent dust formation
Environmental Precautions: Avoid discharge into drains, waterways, or soil
Spill Cleanup Methods: Scoop or sweep up spilled material, collect into suitable container, wash spill area with plenty of water, avoid direct contact
Waste Disposal: Dispose material and solutions using licensed hazardous waste disposal provider, follow local and national regulations

Handling and Storage

Precautions for Safe Handling: Use only with adequate ventilation, avoid breathing dust, prevent contact with skin, eyes, and clothing, do not eat, drink, or smoke during handling, maintain good personal hygiene practices
Safe Storage Conditions: Store in tightly closed, corrosion-resistant container, keep in cool, dry, well-ventilated area, segregate from strong bases, oxidizers, or incompatible chemicals
Storage Temperature: Room temperature preferred, minimize exposure to extremes
Special Storage Practices: Store out of direct sunlight, label containers visibly

Exposure Controls and Personal Protection

Engineering Controls: Use process enclosures, local exhaust ventilation or other engineering controls to keep airborne levels below recommended exposure limits
Exposure Limits: Not established specifically for camphorsulfonic acid; follow standard chemical exposure controls
Personal Protective Equipment—Eyes: Chemical safety goggles or face shield
Personal Protective Equipment—Skin: Chemical-resistant gloves (nitrile, neoprene), lab coat or apron
Personal Protective Equipment—Respiratory: NIOSH-approved respirator for dusts if ventilation is inadequate
General Hygiene: Wash hands and face thoroughly after handling, handle in accordance with laboratory safety protocols

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Slight camphor-like odor
Odor Threshold: No data available
pH (1% Solution): Approximately 2-3
Melting Point: 193–197 °C (379–386 °F)
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, methanol, ethanol, and acetone
Density: About 1.38 g/cm³
Vapor Pressure: Negligible
Evaporation Rate: No data available
Partition Coefficient (Log Pow): Not determined
Other Properties: Non-volatile, non-flammable under normal conditions

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, sensitive to moisture
Reactivity: Reacts with strong bases, may react with oxidizing agents
Incompatible Materials: Strong bases, strong oxidizers, strong reducing agents
Conditions to Avoid: Humidity, moisture, exposure to air for long periods, extreme temperatures
Hazardous Decomposition Products: Sulfur oxides, carbon oxides, other toxic vapors may form during combustion or decomposition
Polymerization: Will not occur under normal conditions

Toxicological Information

Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin (exact LD50 data not widely reported)
Symptoms of Exposure: Causes burning, pain, and irritation on contact; risk of severe eye damage, respiratory tract irritation after inhalation, gastrointestinal distress after ingestion
Chronic Effects: Prolonged or repeated exposure can cause dermatitis or respiratory issues
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or ACGIH
Mutagenicity: No data indicating mutagenic potential
Reproductive Toxicity: No data indicating reproductive harm

Ecological Information

Ecotoxicity: No specific data; based on structure, not expected to bioaccumulate significantly, but strongly acidic nature may pose risk in aquatic environments
Persistence and Degradability: Expected to be biodegradable over time, but acidic nature can disrupt microbial communities during breakdown
Bioaccumulative Potential: Low, based on octanol-water partition
Mobility in Soil: High solubility in water increases mobility, risk of contaminant transport to groundwater
Other Adverse Effects: Avoid uncontrolled release to prevent acidification of local environment or waterways

Disposal Considerations

Waste Disposal Methods: Collect and dispose as hazardous waste in accordance with local, regional, and national regulations
Container Disposal: Decontaminate or triple rinse empty containers before disposal, follow all chemical hygiene guidelines
Special Precautions: Do not discharge untreated material into drains, waterways, or soil; work with hazardous waste management professionals for large volumes
Regulatory Guidance: Consult local environmental authorities for acceptable disposal practices and requirements

Transport Information

UN Number: UN2585
Proper Shipping Name: Camphorsulfonic acid
Transport Hazard Class: 8 (Corrosive materials)
Packing Group: III
Hazard Label: Corrosive
Special Transport Precautions: Transport in fully labeled, tightly closed containers; separate from incompatible goods
Regulations: Subject to ADR, IMDG, IATA, DOT transport guidelines

Regulatory Information

TSCA Status: Listed, subject to chemical inventory regulations
REACH Registration: Substance registered or pre-registered in Europe
SARA Title III: Not listed as an extremely hazardous substance or toxic release
GHS Compliance: Classified according to current United Nations GHS standards
California Proposition 65: Not listed
Substance-Specific Requirements: Use workplace controls and monitor exposure through appropriate policies, ensure correct labeling and documentation according to regional and international guidance, regularly review updates from OSHA, EPA, and global regulatory bodies for new information
Other Regulations: Follow rules from national workplace safety agencies and chemical management laws, update safety data as required by regulation