Product Name: 1,3-Propanesultone
Other Names: 1,2-Epoxypropane-3-sulfonic acid, gamma-Propanesultone
CAS Number: 1120-71-4
Recommended Use: Chemical intermediate, specialty synthesis
Supplier Details: Name, Address, Emergency Contact phone number
Emergency Phone: Emergency hotline specific to region
Classification: Carcinogenicity (Category 1B); Acute toxicity, oral (Category 3); Acute toxicity, inhalation (Category 2); Skin irritation (Category 2); Eye irritation (Category 2A); Mutagenicity (Category 2)
Signal Word: Danger
Hazard Statements: Toxic if swallowed, inhaled, or absorbed through skin. Causes severe skin burns and eye damage. Suspected of causing genetic defects. May cause cancer.
Pictograms: Skull and crossbones, Corrosive, Health hazard
Precautionary Statements: Avoid breathing dust or vapors. Wash hands thoroughly after handling. Use personal protective equipment as required.
Chemical Name: 1,3-Propanesultone
Common Synonyms: Propanesultone, gamma-Propanesultone
CAS Number: 1120-71-4
Concentration: >99%
Impurities or Stabilizers: None significant
Inhalation: Remove person from exposure, seek fresh air, keep comfortable for breathing, consult a physician. If respiratory distress occurs, deliver oxygen.
Skin Contact: Immediately remove contaminated clothing, rinse skin with copious amounts of water for at least 15 minutes, consult a physician.
Eye Contact: Rinse cautiously with water for some time. Remove contact lenses if present and easy to do. Continue rinsing, seek immediate medical attention.
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel. Immediate medical attention required.
Most Important Symptoms: Skin burns, respiratory tract irritation, mucous membrane corrosion, delayed effects may occur
Suitable Extinguishing Media: Water spray, dry chemical, alcohol-resistant foam, carbon dioxide
Hazards from Combustion: Sulfur oxides, carbon monoxide, carbon dioxide, other toxic fumes
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Procedures: Evacuate area, cool exposed containers, avoid contamination of runoff, suppress vapors with water spray
Personal Precautions: Evacuate unnecessary personnel, ventilate area, wear protective gloves, goggles, and clothing
Environmental Precautions: Prevent spillage from entering drains, sewers, or water courses, report large spills to local authorities
Cleanup Methods: Contain spill with inert material, such as sand or earth, collect using non-sparking tools, place in a properly labeled chemical waste container for disposal
Additional Advice: Wash surface thoroughly after material pick-up to remove contamination
Handling: Keep container tightly closed, prevent vapor inhalation, avoid contact with skin, eyes, and clothing, use only in a well-ventilated area, keep away from sources of ignition
Storage Conditions: Store in a cool, dry environment away from heat and sunlight, segregate from acids, bases, and oxidizers, keep in original container, tightly sealed and labeled
Incompatibilities: Avoid contact with strong bases, strong acids, oxidizing agents as violent reactions may occur
Occupational Exposure Limits: No established exposure limit for this compound; treat as highly toxic chemical
Engineering Controls: Use fume hood or local exhaust ventilation, keep area well ventilated
Eye Protection: Chemical safety goggles
Skin Protection: Impervious gloves (nitrile, neoprene), chemical-resistant lab coat
Respiratory Protection: Use NIOSH-approved respirator for organic vapors if exposure risk exists
Other Protection: Provide eye wash stations, emergency showers in work area, do not eat, drink, or smoke while using this material
Appearance: Colorless to pale yellow liquid or crystalline solid
Odor: Mild, characteristic odor
Molecular Formula: C3H6O3S
Molecular Weight: 122.14 g/mol
Melting Point: 28–31°C
Boiling Point: 170–173°C
Flash Point: >100°C
Solubility: Slightly soluble in water, soluble in many organic solvents
Vapor Pressure: 0.3 mmHg at 25°C
Density: 1.33 g/cm³ at 20°C
pH: Not applicable
Partition Coefficient (log Pow): -1.3
Autoignition Temperature: 415°C
Decomposition Temperature: Not determined
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts with strong bases, water slowly hydrolyzes the sultone ring, releasing sulfonic acids
Hazardous Reactions: May polymerize or decompose when exposed to strong bases or acids
Conditions to Avoid: Heat, flames, moisture, contact with incompatible materials
Hazardous Decomposition Products: Sulfur oxides, carbon monoxide, carbon dioxide on burning or thermal decomposition
Acute Toxicity: Toxic by oral, dermal, and inhalation routes; oral LD50 (rat): 89 mg/kg; inhalation LC50 (rat, 4h): 0.72 mg/L
Skin Corrosion/Irritation: Causes severe skin burns and irritation
Serious Eye Damage/Irritation: Produces severe eye irritation, redness, and tissue damage
Respiratory Sensitization: Inhalation irritates respiratory tract
Carcinogenicity: Classified as a Category 1B carcinogen, may cause cancer by inhalation or skin contact
Mutagenicity: Suspected of causing genetic defects
Target Organ Effects: Liver, kidneys, central nervous system, eyes, skin
Symptoms of Exposure: Rash, burning sensation, coughing, headache, muscle weakness, gastrointestinal symptoms
Aquatic Toxicity: Prevent release to waterways; toxic to aquatic life (EC50/LC50 values available for aquatic organisms: daphnia 2.1 mg/L, algae 0.9 mg/L)
Persistence and Degradability: Degradation occurs slowly in water; stable under environmental conditions
Bioaccumulative Potential: Low potential for bioaccumulation (log Pow < 0)
Mobility in Soil: May leach into groundwater from soil
Other Adverse Effects: Releases of sultones can have long-term harmful effects on aquatic environments
Waste Treatment Methods: Use licensed chemical waste disposal contractor; incinerate in regulated facility; do not dispose in ordinary trash or drains
Hazardous Waste Code: Regulated under hazardous waste rules, specific code depends on local or national regulations
Container Disposal: Empty containers retain residue, follow proper disposal procedures for hazardous chemicals
Precautions: Avoid contact with skin, use protective equipment during disposal operations, keep unreacted material separated from incompatible wastes
UN Number: UN 2376
Proper Shipping Name: 1,3-Propanesultone
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: I (high danger)
Environmental Hazards: Marine pollutant
Transport Precautions: Keep container sealed and upright; transport in well-ventilated vehicles; avoid loading with foodstuffs or consumables
OSHA Hazard Communication: Classified as highly hazardous to health; requires workplace controls and labeling
TSCA Status: Listed
SARA: Subject to regulations under CERCLA, SARA Title III Section 313
REACH Registration: Registered under European REACH system, subject to restrictions
California Proposition 65: Listed as a chemical known to cause cancer
Other Regulations: Compliant with GHS classification, EU Directives on dangerous substances, Canadian WHMIS, Australia AICS
Label Requirements: Hazard pictograms, signal words, hazard, and precautionary statements on all containers
