Product Name: 1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-Sulphonic Acid
Chemical Formula: C4F9SO3H
Other Names: Nonafluorobutanesulfonic acid, PFBS
Use: Surfactant, cleaning agent, chemical intermediate in various manufacturing applications
Supplier: Contact relevant chemical suppliers
Emergency Phone: Refer to manufacturer’s or regional poison control contact
Recommended Use Restrictions: Reserved for industrial or professional use only where proper safety protocols are in place
GHS Classification: Acute Toxicity (Oral Category 4), Skin Corrosion/Irritation Category 1B, Eye Damage Category 1, Hazardous to the Aquatic Environment (Acute and Chronic Category 3)
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes severe skin burns and eye damage, harmful to aquatic life with long-lasting effects
Pictograms: Corrosive, Exclamation mark, Environment
Precautionary Statements: Avoid breathing mist/vapours, wear protective gloves and eye/face protection, wash skin thoroughly after handling, do not eat/drink/smoke during use, avoid release to the environment
Chemical Name: 1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-Sulphonic Acid
CAS Number: 375-73-5
EC Number: 206-801-3
Concentration: 95-100%, trace impurities possible
Impurities: Nonafluorobutanesulfonate salts — usually less than 1%
General Advice: Remove contaminated clothing, get fresh air immediately if inhaled
Eye Contact: Rinse with plenty of water for at least 15 minutes, lifting eyelids occasionally; seek medical attention promptly
Skin Contact: Wash affected area thoroughly with soap and water for at least 15 minutes; immediate medical attention may be needed for burns
Inhalation: Move to fresh air, assist breathing if needed, contact medical personnel if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical help
Note to Physician: Treat as substance causing corrosive burns and possible systemic effects
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, alcohol-resistant foam; water spray for larger fires
Unsuitable Media: Direct jet of water may cause chemical splatter
Special Hazards: Toxic and corrosive gases such as sulfur oxides, hydrogen fluoride, carbonyl fluoride may form during combustion
Protective Equipment: Wear self-contained breathing apparatus and chemical-resistant protective clothing
Firefighting Instructions: Prevent run-off from entering waterways or drains, isolate area, evacuate personnel as necessary, ventilate area after fire
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, acid-resistant apron, respiratory protection if vapours present
Environmental Precautions: Avoid release to soil, waterways, or drains
Containment: Stop spill if safe, create dikes using inert material such as sand, absorb with non-combustible material
Cleanup: Collect absorbed material into properly labelled containers, clean remaining residue with water and detergent, dispose according to local regulations
Decontamination: Ventilate affected area, wash surface with water and alkaline detergent
Handling: Wear chemical-resistant gloves, goggles, and protective clothing, use only in well-ventilated areas, avoid contact with skin, eyes, and clothing, prevent aerosol and vapour formation
Hygiene: Wash hands thoroughly after handling, remove contaminated clothing, keep work areas clean, no eating, drinking, or smoking while handling
Storage: Store in tightly closed containers in a cool, dry, well-ventilated location away from incompatible substances, protect from light, separate from strong bases, acids, oxidizing and reducing agents
Incompatibility: Avoid contact with strong bases, strong oxidizers and reducing agents
Engineering Controls: Chemical fume hood or equivalent local exhaust ventilation
Occupational Exposure Limits: No OSHA or ACGIH exposure limits established for this compound, minimize exposure to lowest feasible level
Personal Protective Equipment: Chemical-resistant gloves (such as butyl rubber), splash goggles, laboratory coat or apron, face shield, suitable respiratory protection if exposure limits exceeded
Monitoring: Routine air monitoring recommended in high-use settings
Other Protection: Emergency eyewash and safety shower available in vicinity
Appearance: Colorless to pale yellow liquid
Odor: Not much odor reported
Odor Threshold: Not established
Melting Point: About -12 °C
Boiling Point: About 163 °C at 760 mmHg
Flash Point: Not established, likely non-flammable
Evaporation Rate: Not available
Flammability: No significant flammability expected
Explosive Properties: Not classified as explosive
Vapor Pressure: Low at ambient temperature
Vapor Density: Not established
Relative Density: About 1.6 g/cm³ at 20 °C
Solubility: Highly soluble in water; very low partitioning to organic solvents
pH: Strongly acidic, less than 1 (solution)
Partition Coefficient: Log Kow below zero (hydrophilic)
Decomposition Temperature: Above 200 °C (breakdown may release toxic gases)
Chemical Stability: Remains stable under normal storage conditions
Reactivity: Reacts with strong bases and reducing agents, vigorous reaction with strong oxidizers
Conditions to Avoid: Prolonged heating, incompatibles (strong oxidizers, strong bases, reducing agents)
Hazardous Decomposition Products: Sulfur oxides, hydrogen fluoride, carbonyl fluoride, perfluoroalkyl fragments may form on burning or decomposition
Polymerization: Does not polymerize under normal handling
Acute Toxicity: Oral LD50 (rat) approximately 1,000 mg/kg, causes irritation and burns to digestive tract
Skin Corrosion/Irritation: Causes severe burns, possible ulceration; repeated exposure may worsen effects
Eye Damage/Irritation: Eye contact causes severe pain, redness, and possibly irreversible damage
Sensitization: No known evidence of respiratory or skin sensitization
Long-term Exposure: Animal studies indicate possible liver and kidney effects, no reliable data for carcinogenicity
Mutagenicity and Reproductive Effects: No strong evidence of genotoxic or reproductive toxicity
Routes of Exposure: Contact with skin, ingestion, inhalation of aerosol or vapour
Other Effects: Systemic toxicity possible in high occupational exposure scenarios
Aquatic Toxicity: Harmful to aquatic life, acute LC50 (fish, daphnia) in tens of milligrams per liter
Persistence: Very persistent in the environment, does not break down readily
Bioaccumulation Potential: Moderate, but lower than long-chain PFAS compounds
Mobility in Soil: High water solubility leads to significant leaching potential
Secondary Effects: May cause long-term effects on aquatic organisms, potential to spread widely from point sources
Degradation: Resistant to typical microbial degradation, not easily removed by conventional water treatment
Waste Treatment Methods: Disposal through incineration at high temperatures in facilities equipped with scrubbers for fluorine-containing gases, landfilling only if allowed under local regulations
Contaminated Packaging: Rinse thoroughly and send to approved waste handlers; avoid reusing containers
Special Disposal Precautions: Keep spilled product and waste out of drains and sewers, comply with local, national, and international disposal regulations
Waste Code: Assign based on mixture and use scenario, generally hazardous chemical waste
UN Number: UN 3265 (Potentially, as it is a corrosive liquid)
Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (may use chemical’s name under IMDG/IATA)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II or III (depends on test data and jurisdiction)
Marine Pollutant: Recognized risk to aquatic environments
Special Precautions: Zero tolerance for leaks, use compatible packaging materials, segregate from incompatible substances, clearly label all containers
TSCA: Listed, reporting and recordkeeping required in the US
REACH: Registered or subject to notification in the EU
OSHA: Hazardous per hazard communication standard
SARA 313: Not on list; other PFAS regulations may apply
Canada DSL/NDSL: Listed
Japan ENCS: Listed
China IECSC: Listed
California Prop 65: Not currently identified, but review regulatory updates for PFAS
Global Regulations: Subject to import, use, and disposal controls under multiple regional frameworks; ongoing assessment due to environmental persistence concerns
